3lsv

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{{Seed}}
 
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[[Image:3lsv.jpg|left|200px]]
 
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==Structure of the A237F mutant of the pentameric ligand gated ion channel from Gloeobacter Violaceus==
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The line below this paragraph, containing "STRUCTURE_3lsv", creates the "Structure Box" on the page.
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<StructureSection load='3lsv' size='340' side='right'caption='[[3lsv]], [[Resolution|resolution]] 3.15&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3lsv]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Gloeobacter_violaceus Gloeobacter violaceus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LSV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3LSV FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.15&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3lsv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3lsv OCA], [https://pdbe.org/3lsv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3lsv RCSB], [https://www.ebi.ac.uk/pdbsum/3lsv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3lsv ProSAT]</span></td></tr>
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{{STRUCTURE_3lsv| PDB=3lsv | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/GLIC_GLOVI GLIC_GLOVI] Cationic channel with similar permeabilities for Na(+) and K(+), that is activated by an increase of the proton concentration on the extracellular side. Displays no permeability for chloride ions. Shows slow kinetics of activation, no desensitization and a single channel conductance of 8 pS. Might contribute to adaptation to external pH change.<ref>PMID:17167423</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ls/3lsv_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3lsv ConSurf].
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<div style="clear:both"></div>
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===Structure of the A237F mutant of the pentameric ligand gated ion channel from Gloeobacter Violaceus===
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==See Also==
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*[[Ion channels 3D structures|Ion channels 3D structures]]
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== References ==
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<references/>
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The line below this paragraph, {{ABSTRACT_PUBMED_20308576}}, adds the Publication Abstract to the page
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__TOC__
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(as it appears on PubMed at http://www.pubmed.gov), where 20308576 is the PubMed ID number.
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</StructureSection>
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{{ABSTRACT_PUBMED_20308576}}
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==About this Structure==
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3LSV is a 5 chains structure with sequences from [http://en.wikipedia.org/wiki/Gloeobacter_violaceus Gloeobacter violaceus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LSV OCA].
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==Reference==
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<ref group="xtra">PMID:20308576</ref><references group="xtra"/>
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[[Category: Gloeobacter violaceus]]
[[Category: Gloeobacter violaceus]]
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[[Category: Corringer, P J.]]
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[[Category: Large Structures]]
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[[Category: Delarue, M.]]
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[[Category: Corringer PJ]]
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[[Category: Nury, H.]]
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[[Category: Delarue M]]
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[[Category: Channel]]
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[[Category: Nury H]]
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[[Category: Cys-loop]]
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[[Category: Membrane protein]]
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[[Category: Plgic]]
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[[Category: Transport protein]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Apr 28 10:51:05 2010''
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Current revision

Structure of the A237F mutant of the pentameric ligand gated ion channel from Gloeobacter Violaceus

PDB ID 3lsv

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OCA

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