3lzc

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{{Seed}}
 
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[[Image:3lzc.jpg|left|200px]]
 
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==Crystal structure of Dph2 from Pyrococcus horikoshii==
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The line below this paragraph, containing "STRUCTURE_3lzc", creates the "Structure Box" on the page.
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<StructureSection load='3lzc' size='340' side='right'caption='[[3lzc]], [[Resolution|resolution]] 2.26&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3lzc]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_horikoshii Pyrococcus horikoshii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LZC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3LZC FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.261&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3lzc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3lzc OCA], [https://pdbe.org/3lzc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3lzc RCSB], [https://www.ebi.ac.uk/pdbsum/3lzc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3lzc ProSAT]</span></td></tr>
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{{STRUCTURE_3lzc| PDB=3lzc | SCENE= }}
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</table>
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== Function ==
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===Crystal structure of Dph2 from Pyrococcus horikoshii===
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[https://www.uniprot.org/uniprot/DPH2_PYRHO DPH2_PYRHO] Catalyzes the first step of diphthamide biosynthesis, i.e. the transfer of the 3-amino-3-carboxypropyl group from S-adenosyl-L-methionine (SAM) to the C2 position of the imidazole ring of the target histidine residue in translation elongation factor 2 (EF-2).<ref>PMID:20559380</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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==About this Structure==
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Check<jmol>
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3LZC is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Pyrococcus_horikoshii Pyrococcus horikoshii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LZC OCA].
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/lz/3lzc_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3lzc ConSurf].
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<div style="clear:both"></div>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Pyrococcus horikoshii]]
[[Category: Pyrococcus horikoshii]]
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[[Category: Dzikovski, B.]]
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[[Category: Dzikovski B]]
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[[Category: Ealick, S E.]]
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[[Category: Ealick SE]]
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[[Category: Freed, J.]]
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[[Category: Freed J]]
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[[Category: Koralewski, R M.]]
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[[Category: Koralewski RM]]
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[[Category: Krebs, C.]]
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[[Category: Krebs C]]
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[[Category: Lee, M.]]
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[[Category: Lee M]]
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[[Category: Lin, H.]]
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[[Category: Lin H]]
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[[Category: Torelli, A T.]]
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[[Category: Torelli AT]]
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[[Category: Wang, E.]]
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[[Category: Wang E]]
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[[Category: Zhang, Y.]]
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[[Category: Zhang Y]]
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[[Category: Zhu, X.]]
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[[Category: Zhu X]]
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[[Category: Biosynthetic protein]]
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[[Category: Diphthamide biosynthesis]]
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[[Category: Gene triplication]]
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[[Category: Radical sam enzyme]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jun 23 08:50:27 2010''
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Current revision

Crystal structure of Dph2 from Pyrococcus horikoshii

PDB ID 3lzc

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