This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


3lzc

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (10:23, 21 February 2024) (edit) (undo)
 
(6 intermediate revisions not shown.)
Line 1: Line 1:
-
{{Seed}}
 
-
[[Image:3lzc.png|left|200px]]
 
-
<!--
+
==Crystal structure of Dph2 from Pyrococcus horikoshii==
-
The line below this paragraph, containing "STRUCTURE_3lzc", creates the "Structure Box" on the page.
+
<StructureSection load='3lzc' size='340' side='right'caption='[[3lzc]], [[Resolution|resolution]] 2.26&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[3lzc]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_horikoshii Pyrococcus horikoshii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LZC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3LZC FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.261&#8491;</td></tr>
-
-->
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3lzc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3lzc OCA], [https://pdbe.org/3lzc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3lzc RCSB], [https://www.ebi.ac.uk/pdbsum/3lzc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3lzc ProSAT]</span></td></tr>
-
{{STRUCTURE_3lzc| PDB=3lzc | SCENE= }}
+
</table>
-
 
+
== Function ==
-
===Crystal structure of Dph2 from Pyrococcus horikoshii===
+
[https://www.uniprot.org/uniprot/DPH2_PYRHO DPH2_PYRHO] Catalyzes the first step of diphthamide biosynthesis, i.e. the transfer of the 3-amino-3-carboxypropyl group from S-adenosyl-L-methionine (SAM) to the C2 position of the imidazole ring of the target histidine residue in translation elongation factor 2 (EF-2).<ref>PMID:20559380</ref>
-
 
+
== Evolutionary Conservation ==
-
 
+
[[Image:Consurf_key_small.gif|200px|right]]
-
<!--
+
Check<jmol>
-
The line below this paragraph, {{ABSTRACT_PUBMED_20559380}}, adds the Publication Abstract to the page
+
<jmolCheckbox>
-
(as it appears on PubMed at http://www.pubmed.gov), where 20559380 is the PubMed ID number.
+
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/lz/3lzc_consurf.spt"</scriptWhenChecked>
-
-->
+
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
-
{{ABSTRACT_PUBMED_20559380}}
+
<text>to colour the structure by Evolutionary Conservation</text>
-
 
+
</jmolCheckbox>
-
==About this Structure==
+
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3lzc ConSurf].
-
3LZC is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Pyrococcus_horikoshii Pyrococcus horikoshii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LZC OCA].
+
<div style="clear:both"></div>
-
 
+
== References ==
-
==Reference==
+
<references/>
-
<ref group="xtra">PMID:20559380</ref><references group="xtra"/>
+
__TOC__
 +
</StructureSection>
 +
[[Category: Large Structures]]
[[Category: Pyrococcus horikoshii]]
[[Category: Pyrococcus horikoshii]]
-
[[Category: Dzikovski, B.]]
+
[[Category: Dzikovski B]]
-
[[Category: Ealick, S E.]]
+
[[Category: Ealick SE]]
-
[[Category: Freed, J.]]
+
[[Category: Freed J]]
-
[[Category: Koralewski, R M.]]
+
[[Category: Koralewski RM]]
-
[[Category: Krebs, C.]]
+
[[Category: Krebs C]]
-
[[Category: Lee, M.]]
+
[[Category: Lee M]]
-
[[Category: Lin, H.]]
+
[[Category: Lin H]]
-
[[Category: Torelli, A T.]]
+
[[Category: Torelli AT]]
-
[[Category: Wang, E.]]
+
[[Category: Wang E]]
-
[[Category: Zhang, Y.]]
+
[[Category: Zhang Y]]
-
[[Category: Zhu, X.]]
+
[[Category: Zhu X]]
-
[[Category: Biosynthetic protein]]
+
-
[[Category: Diphthamide biosynthesis]]
+
-
[[Category: Gene triplication]]
+
-
[[Category: Radical sam enzyme]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 14 15:53:00 2010''
+

Current revision

Crystal structure of Dph2 from Pyrococcus horikoshii

PDB ID 3lzc

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/3lzc"
Personal tools