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3mxa
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 3mxa is ON HOLD Authors: Munoz, I.G., Prieto, J., Subramanian, S., Coloma, J., Montoya, G. Description: Molecular basis of engineered meganuclease ...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Molecular basis of engineered meganuclease targeting of the endogenous human RAG1 locus== | |
| - | + | <StructureSection load='3mxa' size='340' side='right'caption='[[3mxa]], [[Resolution|resolution]] 2.30Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[3mxa]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Chlamydomonas_reinhardtii Chlamydomonas reinhardtii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MXA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3MXA FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3Å</td></tr> | |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1PE:PENTAETHYLENE+GLYCOL'>1PE</scene>, <scene name='pdbligand=EOH:ETHANOL'>EOH</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3mxa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3mxa OCA], [https://pdbe.org/3mxa PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3mxa RCSB], [https://www.ebi.ac.uk/pdbsum/3mxa PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3mxa ProSAT]</span></td></tr> | |
| + | </table> | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/mx/3mxa_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3mxa ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Chlamydomonas reinhardtii]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Coloma J]] | ||
| + | [[Category: Montoya G]] | ||
| + | [[Category: Munoz IG]] | ||
| + | [[Category: Prieto J]] | ||
| + | [[Category: Subramanian S]] | ||
Current revision
Molecular basis of engineered meganuclease targeting of the endogenous human RAG1 locus
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