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3n4p

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{{Seed}}
 
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[[Image:3n4p.jpg|left|200px]]
 
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<!--
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==Human cytomegalovirus terminase nuclease domain==
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The line below this paragraph, containing "STRUCTURE_3n4p", creates the "Structure Box" on the page.
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<StructureSection load='3n4p' size='340' side='right'caption='[[3n4p]], [[Resolution|resolution]] 2.15&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3n4p]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_herpesvirus_5_strain_Towne Human herpesvirus 5 strain Towne]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3N4P OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3N4P FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.15&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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{{STRUCTURE_3n4p| PDB=3n4p | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3n4p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3n4p OCA], [https://pdbe.org/3n4p PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3n4p RCSB], [https://www.ebi.ac.uk/pdbsum/3n4p PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3n4p ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/TRM3_HCMVA TRM3_HCMVA] Component of the molecular motor that translocates genomic DNA in empty capsid during DNA packaging. Heterodimerizes with small terminase protein to be docked on capsid portal protein. The latter forms a ring in which genomic DNA in translocated into the capsid. May have or induce an endonuclease activity to cleave the genome concatemer after encapsidation (By similarity).
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/n4/3n4p_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3n4p ConSurf].
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<div style="clear:both"></div>
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===Human cytomegalovirus terminase nuclease domain===
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==See Also==
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*[[Terminase 3D Structures|Terminase 3D Structures]]
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__TOC__
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<!--
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_20805464}}, adds the Publication Abstract to the page
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[[Category: Human herpesvirus 5 strain Towne]]
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(as it appears on PubMed at http://www.pubmed.gov), where 20805464 is the PubMed ID number.
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[[Category: Large Structures]]
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[[Category: Arnan C]]
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{{ABSTRACT_PUBMED_20805464}}
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[[Category: Blanco AG]]
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[[Category: Coll M]]
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==About this Structure==
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[[Category: Hart DJ]]
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3N4P is a 4 chains structure with sequences from [http://en.wikipedia.org/wiki/Human_herpesvirus_5 Human herpesvirus 5]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3N4P OCA].
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[[Category: Mas PJ]]
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[[Category: Nadal M]]
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==Reference==
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[[Category: Sola M]]
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<ref group="xtra">PMID:20805464</ref><references group="xtra"/>
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[[Category: Human herpesvirus 5]]
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[[Category: Arnan, C.]]
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[[Category: Blanco, A G.]]
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[[Category: Coll, M.]]
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[[Category: Hart, D J.]]
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[[Category: Mas, P J.]]
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[[Category: Nadal, M.]]
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[[Category: Sola, M.]]
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[[Category: Dna binding protein]]
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[[Category: Dna packaging]]
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[[Category: Hcmv]]
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[[Category: Herpesvirus]]
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[[Category: Human cytomegalovirus]]
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[[Category: Nuclease]]
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[[Category: Terminase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct 6 06:06:08 2010''
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Current revision

Human cytomegalovirus terminase nuclease domain

PDB ID 3n4p

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