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3nj0

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{{STRUCTURE_3nj0| PDB=3nj0 | SCENE= }}
 
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===X-ray crystal structure of the PYL2-pyrabactin A complex===
 
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{{ABSTRACT_PUBMED_20729860}}
 
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==Function==
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==X-ray crystal structure of the PYL2-pyrabactin A complex==
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[[http://www.uniprot.org/uniprot/PYL2_ARATH PYL2_ARATH]] Receptor for abscisic acid (ABA) required for ABA-mediated responses such as stomatal closure and germination inhibition. Inhibits the activity of group-A protein phosphatases type 2C (PP2Cs) when activated by ABA.<ref>PMID:19898420</ref> <ref>PMID:19893533</ref>
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<StructureSection load='3nj0' size='340' side='right'caption='[[3nj0]], [[Resolution|resolution]] 1.89&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3nj0]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NJ0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3NJ0 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.89&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PYV:4-BROMO-N-(PYRIDIN-2-YLMETHYL)NAPHTHALENE-1-SULFONAMIDE'>PYV</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3nj0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nj0 OCA], [https://pdbe.org/3nj0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3nj0 RCSB], [https://www.ebi.ac.uk/pdbsum/3nj0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3nj0 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/PYL2_ARATH PYL2_ARATH] Receptor for abscisic acid (ABA) required for ABA-mediated responses such as stomatal closure and germination inhibition. Inhibits the activity of group-A protein phosphatases type 2C (PP2Cs) when activated by ABA.<ref>PMID:19898420</ref> <ref>PMID:19893533</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/nj/3nj0_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3nj0 ConSurf].
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<div style="clear:both"></div>
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==About this Structure==
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==See Also==
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[[3nj0]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NJ0 OCA].
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*[[Abscisic acid receptor 3D structures|Abscisic acid receptor 3D structures]]
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== References ==
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==Reference==
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<references/>
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<ref group="xtra">PMID:020729860</ref><references group="xtra"/><references/>
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__TOC__
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</StructureSection>
[[Category: Arabidopsis thaliana]]
[[Category: Arabidopsis thaliana]]
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[[Category: Bingman, C A.]]
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[[Category: Large Structures]]
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[[Category: Burgie, E S.]]
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[[Category: Bingman CA]]
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[[Category: CESG, Center for Eukaryotic Structural Genomics.]]
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[[Category: Burgie ES]]
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[[Category: Cutler, S R.]]
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[[Category: Cutler SR]]
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[[Category: Jensen, D R.]]
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[[Category: Jensen DR]]
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[[Category: Peterson, F C.]]
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[[Category: Peterson FC]]
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[[Category: Phillips, G N.]]
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[[Category: Phillips Jr GN]]
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[[Category: Volkman, B F.]]
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[[Category: Volkman BF]]
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[[Category: Aba]]
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[[Category: Center for eukaryotic structural genomic]]
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[[Category: Cesg]]
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[[Category: Hormone receptor]]
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[[Category: Plant hormone]]
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[[Category: Protein structure initiative]]
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[[Category: Psi]]
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[[Category: Pyr/pyl/rcar]]
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[[Category: Start]]
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[[Category: Structural genomic]]
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Current revision

X-ray crystal structure of the PYL2-pyrabactin A complex

PDB ID 3nj0

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