3ogq
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal Structure of 6s-98S FIV Protease with Lopinavir bound== | |
| + | <StructureSection load='3ogq' size='340' side='right'caption='[[3ogq]], [[Resolution|resolution]] 1.80Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[3ogq]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Feline_immunodeficiency_virus Feline immunodeficiency virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OGQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3OGQ FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AB1:N-{1-BENZYL-4-[2-(2,6-DIMETHYL-PHENOXY)-ACETYLAMINO]-3-HYDROXY-5-PHENYL-PENTYL}-3-METHYL-2-(2-OXO-TETRAHYDRO-PYRIMIDIN-1-YL)-BUTYRAMIDE'>AB1</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ogq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ogq OCA], [https://pdbe.org/3ogq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ogq RCSB], [https://www.ebi.ac.uk/pdbsum/3ogq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ogq ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/POL_FIVPE POL_FIVPE] During replicative cycle of retroviruses, the reverse-transcribed viral DNA is integrated into the host chromosome by the viral integrase enzyme. RNase H activity is associated with the reverse transcriptase. | ||
| - | + | ==See Also== | |
| - | + | *[[Immunodeficiency virus protease 3D structures|Immunodeficiency virus protease 3D structures]] | |
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
| - | + | [[Category: Feline immunodeficiency virus]] | |
| + | [[Category: Large Structures]] | ||
| + | [[Category: Elder JH]] | ||
| + | [[Category: Lin Y-C]] | ||
| + | [[Category: Perryman AL]] | ||
| + | [[Category: Stout CD]] | ||
Current revision
Crystal Structure of 6s-98S FIV Protease with Lopinavir bound
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