This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
3ong
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 3ong is ON HOLD Authors: Wang, J., Taherbhoy, A.M., Hunt, H.W., Seyedin, S.N., Miller, D.W., Huang, D.T., Schulman, B.A. Description: Ufd ''Page s...) |
|||
| (14 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of UBA2ufd-Ubc9: insights into E1-E2 interactions in Sumo pathways== | |
| + | <StructureSection load='3ong' size='340' side='right'caption='[[3ong]], [[Resolution|resolution]] 2.30Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[3ong]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ONG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ONG FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3Å</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ong FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ong OCA], [https://pdbe.org/3ong PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ong RCSB], [https://www.ebi.ac.uk/pdbsum/3ong PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ong ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/UBA2_YEAST UBA2_YEAST] The dimeric enzyme acts as a SMT3 E1 ligase. It mediates ATP-dependent activation of SMT3 and formation of a thioester with a conserved cysteine residue on AOS1. | ||
| - | + | ==See Also== | |
| - | + | *[[SUMO conjugating enzyme Ubc9|SUMO conjugating enzyme Ubc9]] | |
| - | + | *[[3D structures of Ubiquitin activating enzyme|3D structures of Ubiquitin activating enzyme]] | |
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
| + | [[Category: Large Structures]] | ||
| + | [[Category: Saccharomyces cerevisiae]] | ||
| + | [[Category: Huang DT]] | ||
| + | [[Category: Hunt HW]] | ||
| + | [[Category: Miller DW]] | ||
| + | [[Category: Schulman BA]] | ||
| + | [[Category: Seyedin SN]] | ||
| + | [[Category: Taherbhoy AM]] | ||
| + | [[Category: Wang J]] | ||
Current revision
Crystal structure of UBA2ufd-Ubc9: insights into E1-E2 interactions in Sumo pathways
| |||||||||||
