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3ong
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| - | {{STRUCTURE_3ong| PDB=3ong | SCENE= }} | ||
| - | ===Crystal structure of UBA2ufd-Ubc9: insights into E1-E2 interactions in Sumo pathways=== | ||
| - | {{ABSTRACT_PUBMED_21209884}} | ||
| - | == | + | ==Crystal structure of UBA2ufd-Ubc9: insights into E1-E2 interactions in Sumo pathways== |
| - | [[ | + | <StructureSection load='3ong' size='340' side='right'caption='[[3ong]], [[Resolution|resolution]] 2.30Å' scene=''> |
| - | + | == Structural highlights == | |
| - | == | + | <table><tr><td colspan='2'>[[3ong]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ONG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ONG FirstGlance]. <br> |
| - | [[3ong]] is a 4 chain structure with sequence from [ | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3Å</td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ong FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ong OCA], [https://pdbe.org/3ong PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ong RCSB], [https://www.ebi.ac.uk/pdbsum/3ong PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ong ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/UBA2_YEAST UBA2_YEAST] The dimeric enzyme acts as a SMT3 E1 ligase. It mediates ATP-dependent activation of SMT3 and formation of a thioester with a conserved cysteine residue on AOS1. | ||
==See Also== | ==See Also== | ||
*[[SUMO conjugating enzyme Ubc9|SUMO conjugating enzyme Ubc9]] | *[[SUMO conjugating enzyme Ubc9|SUMO conjugating enzyme Ubc9]] | ||
| - | *[[Ubiquitin activating enzyme|Ubiquitin activating enzyme]] | + | *[[3D structures of Ubiquitin activating enzyme|3D structures of Ubiquitin activating enzyme]] |
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
| - | < | + | [[Category: Large Structures]] |
[[Category: Saccharomyces cerevisiae]] | [[Category: Saccharomyces cerevisiae]] | ||
| - | [[Category: Huang | + | [[Category: Huang DT]] |
| - | [[Category: Hunt | + | [[Category: Hunt HW]] |
| - | [[Category: Miller | + | [[Category: Miller DW]] |
| - | [[Category: Schulman | + | [[Category: Schulman BA]] |
| - | [[Category: Seyedin | + | [[Category: Seyedin SN]] |
| - | [[Category: Taherbhoy | + | [[Category: Taherbhoy AM]] |
| - | [[Category: Wang | + | [[Category: Wang J]] |
| - | + | ||
Current revision
Crystal structure of UBA2ufd-Ubc9: insights into E1-E2 interactions in Sumo pathways
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