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3ooy

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<StructureSection load='3ooy' size='340' side='right'caption='[[3ooy]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
<StructureSection load='3ooy' size='340' side='right'caption='[[3ooy]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3ooy]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OOY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3OOY FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3ooy]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OOY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3OOY FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=TPP:THIAMINE+DIPHOSPHATE'>TPP</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.05&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">TKT ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=TPP:THIAMINE+DIPHOSPHATE'>TPP</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Transketolase Transketolase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.2.1.1 2.2.1.1] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ooy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ooy OCA], [https://pdbe.org/3ooy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ooy RCSB], [https://www.ebi.ac.uk/pdbsum/3ooy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ooy ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ooy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ooy OCA], [https://pdbe.org/3ooy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ooy RCSB], [https://www.ebi.ac.uk/pdbsum/3ooy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ooy ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/TKT_HUMAN TKT_HUMAN]] Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
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[https://www.uniprot.org/uniprot/TKT_HUMAN TKT_HUMAN] Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
==See Also==
==See Also==
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*[[Transketolase|Transketolase]]
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*[[Transketolase 3D structures|Transketolase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Transketolase]]
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[[Category: Arrowsmith CH]]
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[[Category: Arrowsmith, C H]]
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[[Category: Bountra C]]
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[[Category: Bountra, C]]
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[[Category: Chaikuad A]]
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[[Category: Chaikuad, A]]
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[[Category: Edwards A]]
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[[Category: Delft, F von]]
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[[Category: Guo K]]
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[[Category: Edwards, A]]
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[[Category: Kavanagh K]]
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[[Category: Guo, K]]
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[[Category: Kochan G]]
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[[Category: Kavanagh, K]]
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[[Category: Krojer T]]
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[[Category: Kochan, G]]
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[[Category: Krysztofinska E]]
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[[Category: Krojer, T]]
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[[Category: Oppermann U]]
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[[Category: Krysztofinska, E]]
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[[Category: Pilka E]]
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[[Category: Oppermann, U]]
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[[Category: Vollmar M]]
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[[Category: Pilka, E]]
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[[Category: Weigelt J]]
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[[Category: Structural genomic]]
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[[Category: Von Delft F]]
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[[Category: Vollmar, M]]
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[[Category: Weigelt, J]]
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[[Category: Sgc]]
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[[Category: Transferase]]
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Current revision

Crystal structure of human Transketolase (TKT)

PDB ID 3ooy

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