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3opy
From Proteopedia
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| - | [[Image:3opy.png|left|200px]] | ||
| - | + | ==Crystal structure of Pichia pastoris phosphofructokinase in the T-state== | |
| - | + | <StructureSection load='3opy' size='340' side='right'caption='[[3opy]], [[Resolution|resolution]] 3.05Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[3opy]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Komagataella_pastoris_DSMZ_70382 Komagataella pastoris DSMZ 70382]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OPY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3OPY FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.05Å</td></tr> | |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |
| - | == | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3opy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3opy OCA], [https://pdbe.org/3opy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3opy RCSB], [https://www.ebi.ac.uk/pdbsum/3opy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3opy ProSAT]</span></td></tr> |
| - | [[3opy]] is a 12 chain structure | + | </table> |
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/PFKA1_PICPA PFKA1_PICPA] Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.[HAMAP-Rule:MF_03184]<ref>PMID:12125050</ref> | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/op/3opy_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3opy ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
==See Also== | ==See Also== | ||
| - | *[[Phosphofructokinase | + | *[[Phosphofructokinase 3D structures|Phosphofructokinase 3D structures]] |
| - | + | == References == | |
| - | == | + | <references/> |
| - | < | + | __TOC__ |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: | + | [[Category: Komagataella pastoris DSMZ 70382]] |
| - | [[Category: Bruser | + | [[Category: Large Structures]] |
| - | [[Category: Keim | + | [[Category: Bruser A]] |
| - | [[Category: Kirchberger | + | [[Category: Keim A]] |
| - | [[Category: Kloos | + | [[Category: Kirchberger J]] |
| - | [[Category: Kuettner | + | [[Category: Kloos M]] |
| - | [[Category: Marek | + | [[Category: Kuettner EB]] |
| - | [[Category: Schoneberg | + | [[Category: Marek S]] |
| - | [[Category: Strater | + | [[Category: Schoneberg T]] |
| - | + | [[Category: Strater N]] | |
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Current revision
Crystal structure of Pichia pastoris phosphofructokinase in the T-state
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