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3phe

From Proteopedia

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[[Image:3phe.png|left|200px]]
 
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{{STRUCTURE_3phe| PDB=3phe | SCENE= }}
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==HCV NS5B with a bound quinolone inhibitor==
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<StructureSection load='3phe' size='340' side='right'caption='[[3phe]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
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===HCV NS5B with a bound quinolone inhibitor===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3phe]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Hepacivirus_C Hepacivirus C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PHE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3PHE FirstGlance]. <br>
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{{ABSTRACT_PUBMED_21145235}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=C9A:4-CHLOROBENZYL+6-FLUORO-7-(4-METHYLPIPERAZIN-1-YL)-1-[4-(METHYLSULFONYL)BENZYL]-4-OXO-1,4-DIHYDROQUINOLINE-3-CARBOXYLATE'>C9A</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3phe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3phe OCA], [https://pdbe.org/3phe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3phe RCSB], [https://www.ebi.ac.uk/pdbsum/3phe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3phe ProSAT]</span></td></tr>
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[[3phe]] is a 4 chain structure of [[Nonstructural protein]] with sequence from [http://en.wikipedia.org/wiki/Hepatitis_c_virus Hepatitis c virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PHE OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/D0PY27_9HEPC D0PY27_9HEPC]
==See Also==
==See Also==
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*[[Nonstructural protein|Nonstructural protein]]
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*[[Nonstructural protein 3D structures|Nonstructural protein 3D structures]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:021145235</ref><references group="xtra"/>
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[[Category: Hepacivirus C]]
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[[Category: Hepatitis c virus]]
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[[Category: Large Structures]]
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[[Category: Lehoux, I.]]
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[[Category: Lehoux I]]
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[[Category: Somoza, J R.]]
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[[Category: Somoza JR]]
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[[Category: To, N.]]
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[[Category: To N]]
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[[Category: Mitochondrial membrane]]
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[[Category: Polymerase]]
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[[Category: Rna]]
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[[Category: Transferase]]
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[[Category: Transferase-transferase inhibitor complex]]
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Current revision

HCV NS5B with a bound quinolone inhibitor

PDB ID 3phe

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OCA

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