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3pwi

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==Crystal structure of the mutant P34A of D-Glucarate dehydratase from Escherichia coli complexed with product 5-keto-4-deoxy-D-Glucarate==
==Crystal structure of the mutant P34A of D-Glucarate dehydratase from Escherichia coli complexed with product 5-keto-4-deoxy-D-Glucarate==
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<StructureSection load='3pwi' size='340' side='right' caption='[[3pwi]], [[Resolution|resolution]] 2.23&Aring;' scene=''>
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<StructureSection load='3pwi' size='340' side='right'caption='[[3pwi]], [[Resolution|resolution]] 2.23&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3pwi]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PWI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3PWI FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3pwi]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_O157:H7_str._EC4042 Escherichia coli O157:H7 str. EC4042]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PWI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3PWI FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GLR:2,3-DIHYDROXY-5-OXO-HEXANEDIOATE'>GLR</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene><br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2296&#8491;</td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1ec8|1ec8]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GLR:2,3-DIHYDROXY-5-OXO-HEXANEDIOATE'>GLR</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ECH74042_A2717 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3pwi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pwi OCA], [https://pdbe.org/3pwi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3pwi RCSB], [https://www.ebi.ac.uk/pdbsum/3pwi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3pwi ProSAT]</span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3pwi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pwi OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3pwi RCSB], [http://www.ebi.ac.uk/pdbsum/3pwi PDBsum]</span></td></tr>
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</table>
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<table>
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== Function ==
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[https://www.uniprot.org/uniprot/GUDD_ECOLI GUDD_ECOLI] Catalyzes the dehydration of glucarate to 5-keto-4-deoxy-D-glucarate (5-kdGluc). Also acts on L-idarate.
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Escherichia coli]]
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[[Category: Escherichia coli O157:H7 str. EC4042]]
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[[Category: Almo, S C.]]
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[[Category: Large Structures]]
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[[Category: Fedorov, A A.]]
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[[Category: Almo SC]]
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[[Category: Fedorov, E V.]]
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[[Category: Fedorov AA]]
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[[Category: Gerlt, J A.]]
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[[Category: Fedorov EV]]
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[[Category: Lukk, T.]]
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[[Category: Gerlt JA]]
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[[Category: 5-keto-4-deoxy-d-glucarate]]
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[[Category: Lukk T]]
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[[Category: D-glucarate dehydratase]]
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[[Category: Enolase superfamily fold]]
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[[Category: Lyase]]
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Current revision

Crystal structure of the mutant P34A of D-Glucarate dehydratase from Escherichia coli complexed with product 5-keto-4-deoxy-D-Glucarate

PDB ID 3pwi

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