3q3s
From Proteopedia
(Difference between revisions)
m (Protected "3q3s" [edit=sysop:move=sysop]) |
|||
| (7 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==EthR from Mycobacterium tuberculosis in complex with compound BDM5683== | |
| + | <StructureSection load='3q3s' size='340' side='right'caption='[[3q3s]], [[Resolution|resolution]] 2.00Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[3q3s]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q3S OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3Q3S FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=O8B:2-(2-METHYLPHENOXY)-N-[2-(4-METHYLPHENYL)-2H-BENZOTRIAZOL-5-YL]ACETAMIDE'>O8B</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3q3s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3q3s OCA], [https://pdbe.org/3q3s PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3q3s RCSB], [https://www.ebi.ac.uk/pdbsum/3q3s PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3q3s ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/ETHR_MYCTU ETHR_MYCTU] Involved in the repression of the monooxygenase EthA which is responsible of the formation of the active metabolite of ethionamide (ETH).<ref>PMID:10869356</ref> <ref>PMID:10944230</ref> | ||
| - | + | ==See Also== | |
| - | + | *[[Tetracycline repressor protein 3D structures|Tetracycline repressor protein 3D structures]] | |
| - | + | == References == | |
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Mycobacterium tuberculosis]] | ||
| + | [[Category: Lens Z]] | ||
| + | [[Category: Villeret V]] | ||
| + | [[Category: Willand N]] | ||
Current revision
EthR from Mycobacterium tuberculosis in complex with compound BDM5683
| |||||||||||
