3q3s

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[[Image:3q3s.jpg|left|200px]]
 
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==EthR from Mycobacterium tuberculosis in complex with compound BDM5683==
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The line below this paragraph, containing "STRUCTURE_3q3s", creates the "Structure Box" on the page.
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<StructureSection load='3q3s' size='340' side='right'caption='[[3q3s]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3q3s]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q3S OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3Q3S FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=O8B:2-(2-METHYLPHENOXY)-N-[2-(4-METHYLPHENYL)-2H-BENZOTRIAZOL-5-YL]ACETAMIDE'>O8B</scene></td></tr>
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{{STRUCTURE_3q3s| PDB=3q3s | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3q3s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3q3s OCA], [https://pdbe.org/3q3s PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3q3s RCSB], [https://www.ebi.ac.uk/pdbsum/3q3s PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3q3s ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/ETHR_MYCTU ETHR_MYCTU] Involved in the repression of the monooxygenase EthA which is responsible of the formation of the active metabolite of ethionamide (ETH).<ref>PMID:10869356</ref> <ref>PMID:10944230</ref>
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===EthR from Mycobacterium tuberculosis in complex with compound BDM5683===
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==See Also==
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*[[Tetracycline repressor protein 3D structures|Tetracycline repressor protein 3D structures]]
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== References ==
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==About this Structure==
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<references/>
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[[3q3s]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q3S OCA].
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Mycobacterium tuberculosis]]
[[Category: Mycobacterium tuberculosis]]
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[[Category: Lens, Z.]]
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[[Category: Lens Z]]
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[[Category: Villeret, V.]]
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[[Category: Villeret V]]
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[[Category: Willand, N.]]
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[[Category: Willand N]]
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[[Category: Antitubercular agent]]
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[[Category: Dna-binding protein]]
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[[Category: Repressor protein]]
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[[Category: Transcription repressor-inhibitor complex]]
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[[Category: Tuberculosis]]
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Current revision

EthR from Mycobacterium tuberculosis in complex with compound BDM5683

PDB ID 3q3s

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