This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
3q5k
From Proteopedia
(Difference between revisions)
| (2 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
==Crystal structure of the amino-terminal domain of HSP90 from Leishmania major, LMJF33.0312:M1-K213 in the presence of an inhibitor== | ==Crystal structure of the amino-terminal domain of HSP90 from Leishmania major, LMJF33.0312:M1-K213 in the presence of an inhibitor== | ||
| - | <StructureSection load='3q5k' size='340' side='right' caption='[[3q5k]], [[Resolution|resolution]] 2.35Å' scene=''> | + | <StructureSection load='3q5k' size='340' side='right'caption='[[3q5k]], [[Resolution|resolution]] 2.35Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3q5k]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[3q5k]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Leishmania_major Leishmania major]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q5K OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3Q5K FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=D1U:4-[6,6-DIMETHYL-4-OXO-3-(TRIFLUOROMETHYL)-4,5,6,7-TETRAHYDRO-1H-INDAZOL-1-YL]-2-{[2-(METHYLSULFANYL)ETHYL]AMINO}BENZAMIDE'>D1U</scene> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.35Å</td></tr> |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=D1U:4-[6,6-DIMETHYL-4-OXO-3-(TRIFLUOROMETHYL)-4,5,6,7-TETRAHYDRO-1H-INDAZOL-1-YL]-2-{[2-(METHYLSULFANYL)ETHYL]AMINO}BENZAMIDE'>D1U</scene></td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3q5k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3q5k OCA], [https://pdbe.org/3q5k PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3q5k RCSB], [https://www.ebi.ac.uk/pdbsum/3q5k PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3q5k ProSAT]</span></td></tr> | |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/Q4Q4I6_LEIMA Q4Q4I6_LEIMA] | ||
==See Also== | ==See Also== | ||
| - | *[[Heat Shock | + | *[[Heat Shock Protein structures|Heat Shock Protein structures]] |
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: Arrowsmith | + | [[Category: Leishmania major]] |
| - | [[Category: Bountra | + | [[Category: Arrowsmith CH]] |
| - | [[Category: Cossar | + | [[Category: Bountra C]] |
| - | [[Category: Edwards | + | [[Category: Cossar D]] |
| - | [[Category: Fairlamb | + | [[Category: Edwards AM]] |
| - | [[Category: Ferguson | + | [[Category: Fairlamb A]] |
| - | [[Category: Hills | + | [[Category: Ferguson MAJ]] |
| - | [[Category: Hui | + | [[Category: Hills T]] |
| - | [[Category: Hutchinson | + | [[Category: Hui R]] |
| - | [[Category: Lin | + | [[Category: Hutchinson A]] |
| - | [[Category: MacKenzie | + | [[Category: Lin YH]] |
| - | [[Category: Pizarro | + | [[Category: MacKenzie F]] |
| - | + | [[Category: Pizarro JC]] | |
| - | [[Category: Schapira | + | [[Category: Schapira M]] |
| - | [[Category: Tempel | + | [[Category: Tempel W]] |
| - | [[Category: Weigelt | + | [[Category: Weigelt J]] |
| - | [[Category: Wernimont | + | [[Category: Wernimont AK]] |
| - | [[Category: Zhao | + | [[Category: Zhao Y]] |
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
Current revision
Crystal structure of the amino-terminal domain of HSP90 from Leishmania major, LMJF33.0312:M1-K213 in the presence of an inhibitor
| |||||||||||
Categories: Large Structures | Leishmania major | Arrowsmith CH | Bountra C | Cossar D | Edwards AM | Fairlamb A | Ferguson MAJ | Hills T | Hui R | Hutchinson A | Lin YH | MacKenzie F | Pizarro JC | Schapira M | Tempel W | Weigelt J | Wernimont AK | Zhao Y
