This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


3q7g

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (10:46, 21 February 2024) (edit) (undo)
 
(4 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:3q7g.png|left|200px]]
 
-
<!--
+
==Crystal Structure of E2 domain of Human Amyloid Precursor-Like Protein 1 in complex with SOS (sucrose octasulfate)==
-
The line below this paragraph, containing "STRUCTURE_3q7g", creates the "Structure Box" on the page.
+
<StructureSection load='3q7g' size='340' side='right'caption='[[3q7g]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[3q7g]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q7G OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3Q7G FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
-
-->
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GU4:2,3,4,6-TETRA-O-SULFONATO-ALPHA-D-GLUCOPYRANOSE'>GU4</scene>, <scene name='pdbligand=PRD_900013:sucrose+octasulfate'>PRD_900013</scene>, <scene name='pdbligand=YYJ:1,3,4,6-tetra-O-sulfo-beta-D-fructofuranose'>YYJ</scene></td></tr>
-
{{STRUCTURE_3q7g| PDB=3q7g | SCENE= }}
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3q7g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3q7g OCA], [https://pdbe.org/3q7g PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3q7g RCSB], [https://www.ebi.ac.uk/pdbsum/3q7g PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3q7g ProSAT]</span></td></tr>
-
 
+
</table>
-
===Crystal Structure of E2 domain of Human Amyloid Precursor-Like Protein 1 in complex with SOS (sucrose octasulfate)===
+
== Function ==
-
 
+
[https://www.uniprot.org/uniprot/APLP1_HUMAN APLP1_HUMAN] May play a role in postsynaptic function. The C-terminal gamma-secretase processed fragment, ALID1, activates transcription activation through APBB1 (Fe65) binding (By similarity). Couples to JIP signal transduction through C-terminal binding. May interact with cellular G-protein signaling pathways. Can regulate neurite outgrowth through binding to components of the extracellular matrix such as heparin and collagen I. The gamma-CTF peptide, C30, is a potent enhancer of neuronal apoptosis.
-
 
+
__TOC__
-
<!--
+
</StructureSection>
-
The line below this paragraph, {{ABSTRACT_PUBMED_21715329}}, adds the Publication Abstract to the page
+
-
(as it appears on PubMed at http://www.pubmed.gov), where 21715329 is the PubMed ID number.
+
-
-->
+
-
{{ABSTRACT_PUBMED_21715329}}
+
-
 
+
-
==About this Structure==
+
-
[[3q7g]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q7G OCA].
+
-
 
+
-
==Reference==
+
-
<ref group="xtra">PMID:021715329</ref><references group="xtra"/>
+
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
-
[[Category: Ha, Y.]]
+
[[Category: Large Structures]]
-
[[Category: Xue, Y.]]
+
[[Category: Ha Y]]
-
[[Category: Alzheimer's disease]]
+
[[Category: Xue Y]]
-
[[Category: Amyloid beta precursor protein]]
+
-
[[Category: E2 domain]]
+
-
[[Category: Heparin]]
+
-
[[Category: Signaling]]
+
-
[[Category: Signaling protein]]
+

Current revision

Crystal Structure of E2 domain of Human Amyloid Precursor-Like Protein 1 in complex with SOS (sucrose octasulfate)

PDB ID 3q7g

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/3q7g"
Personal tools