3qik

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[[Image:3qik.jpg|left|200px]]
 
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==Crystal structure of the first PDZ domain of PREX1==
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The line below this paragraph, containing "STRUCTURE_3qik", creates the "Structure Box" on the page.
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<StructureSection load='3qik' size='340' side='right'caption='[[3qik]], [[Resolution|resolution]] 2.29&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3qik]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QIK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3QIK FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.285&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr>
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{{STRUCTURE_3qik| PDB=3qik | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3qik FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qik OCA], [https://pdbe.org/3qik PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3qik RCSB], [https://www.ebi.ac.uk/pdbsum/3qik PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3qik ProSAT]</span></td></tr>
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</table>
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===Crystal structure of the first PDZ domain of PREX1===
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== Function ==
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[https://www.uniprot.org/uniprot/PREX1_HUMAN PREX1_HUMAN] Functions as a RAC guanine nucleotide exchange factor (GEF), which activates the Rac proteins by exchanging bound GDP for free GTP. Its activity is synergistically activated by phosphatidylinositol 3,4,5-trisphosphate and the beta gamma subunits of heterotrimeric G protein. May function downstream of heterotrimeric G proteins in neutrophils.
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__TOC__
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==About this Structure==
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</StructureSection>
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[[3qik]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QIK OCA].
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Arrowsmith, C H.]]
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[[Category: Large Structures]]
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[[Category: Bountra, C.]]
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[[Category: Arrowsmith CH]]
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[[Category: Edwards, A M.]]
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[[Category: Bountra C]]
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[[Category: Li, Y.]]
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[[Category: Edwards AM]]
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[[Category: Park, H.]]
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[[Category: Li Y]]
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[[Category: SGC, Structural Genomics Consortium.]]
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[[Category: Park H]]
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[[Category: Shen, L.]]
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[[Category: Shen L]]
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[[Category: Tempel, W.]]
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[[Category: Tempel W]]
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[[Category: Tong, Y.]]
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[[Category: Tong Y]]
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[[Category: Weigelt, J.]]
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[[Category: Weigelt J]]

Current revision

Crystal structure of the first PDZ domain of PREX1

PDB ID 3qik

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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