This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


3qwl

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (10:50, 21 February 2024) (edit) (undo)
 
(5 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:3qwl.jpg|left|200px]]
 
-
<!--
+
==Crystal structure of human TBC1 domain family member 7==
-
The line below this paragraph, containing "STRUCTURE_3qwl", creates the "Structure Box" on the page.
+
<StructureSection load='3qwl' size='340' side='right'caption='[[3qwl]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[3qwl]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QWL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3QWL FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
-
-->
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr>
-
{{STRUCTURE_3qwl| PDB=3qwl | SCENE= }}
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3qwl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qwl OCA], [https://pdbe.org/3qwl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3qwl RCSB], [https://www.ebi.ac.uk/pdbsum/3qwl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3qwl ProSAT]</span></td></tr>
-
 
+
</table>
-
===Crystal structure of human TBC1 domain family member 7===
+
== Function ==
-
 
+
[https://www.uniprot.org/uniprot/TBCD7_HUMAN TBCD7_HUMAN] Component of the TSC-TBC complex, that contains TBC1D7 in addition to the TSC1-TSC2 complex and consists of the functional complex possessing GTPase-activating protein (GAP) activity toward RHEB in response to alterations in specific cellular growth conditions. The small GTPase RHEB is a direct activator of the protein kinase activity of mTORC1 and the TSC-TBC complex acts as a negative regulator of mTORC1 signaling cascade by acting as a GAP for RHEB. Participates in the proper sensing of growth factors and glucose, but not amino acids, by mTORC1. It is unclear whether TBC1D7 acts as a GTPase-activating protein and additional studies are required to answer this question.<ref>PMID:22795129</ref>
-
 
+
== References ==
-
==About this Structure==
+
<references/>
-
[[3qwl]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QWL OCA].
+
__TOC__
 +
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
-
[[Category: Arrowsmith, C H.]]
+
[[Category: Large Structures]]
-
[[Category: Bountra, C.]]
+
[[Category: Arrowsmith CH]]
-
[[Category: Edwards, A M.]]
+
[[Category: Bountra C]]
-
[[Category: Guan, X.]]
+
[[Category: Edwards AM]]
-
[[Category: Landry, R.]]
+
[[Category: Guan X]]
-
[[Category: Park, H.]]
+
[[Category: Landry R]]
-
[[Category: SGC, Structural Genomics Consortium.]]
+
[[Category: Park H]]
-
[[Category: Tempel, W.]]
+
[[Category: Tempel W]]
-
[[Category: Tong, Y.]]
+
[[Category: Tong Y]]
-
[[Category: Weigelt, J.]]
+
[[Category: Weigelt J]]
-
[[Category: Wernimont, A K.]]
+
[[Category: Wernimont AK]]

Current revision

Crystal structure of human TBC1 domain family member 7

PDB ID 3qwl

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/3qwl"
Personal tools