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3qyx

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[[Image:3qyx.jpg|left|200px]]
 
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==Crystal structure of Mycobacterium tuberculosis EspR in complex with a small DNA fragment==
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The line below this paragraph, containing "STRUCTURE_3qyx", creates the "Structure Box" on the page.
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<StructureSection load='3qyx' size='340' side='right'caption='[[3qyx]], [[Resolution|resolution]] 3.75&Aring;' scene=''>
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3qyx]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QYX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3QYX FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.75&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3qyx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qyx OCA], [https://pdbe.org/3qyx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3qyx RCSB], [https://www.ebi.ac.uk/pdbsum/3qyx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3qyx ProSAT]</span></td></tr>
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{{STRUCTURE_3qyx| PDB=3qyx | SCENE= }}
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</table>
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== Function ==
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===Crystal structure of Mycobacterium tuberculosis EspR in complex with a small DNA fragment===
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[https://www.uniprot.org/uniprot/ESPR_MYCTU ESPR_MYCTU] Virulence regulator that has both architectural and regulatory roles. Impacts cell wall functions and pathogenesis through regulation of multiple genes, including the espACD operon, which is a key ESX-1 component. Influences target gene expression positively or negatively, depending on its binding position relative to the genes it controls. Acts by binding directly to the DNA. May play a central role in regulating virulence gene expression.<ref>PMID:18685700</ref> <ref>PMID:22389481</ref> <ref>PMID:22479184</ref> <ref>PMID:21883526</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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(as it appears on PubMed at http://www.pubmed.gov), where 21883526 is the PubMed ID number.
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[[Category: Large Structures]]
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[[Category: Mycobacterium tuberculosis H37Rv]]
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{{ABSTRACT_PUBMED_21883526}}
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[[Category: Blasco B]]
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[[Category: Cole ST]]
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==About this Structure==
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[[Category: Pojer F]]
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[[3qyx]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QYX OCA].
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==Reference==
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<ref group="xtra">PMID:021883526</ref><references group="xtra"/>
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[[Category: Mycobacterium tuberculosis]]
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[[Category: Blasco, B.]]
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[[Category: Cole, S T.]]
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[[Category: Pojer, F.]]
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[[Category: C-terminal dimerization domain]]
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[[Category: Dimer of dimers binding dna]]
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[[Category: Dna-binding]]
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[[Category: N-terminal hth motif]]
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[[Category: Transcription activator]]
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[[Category: Transcription factor]]
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[[Category: Transcription-dna complex]]
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Current revision

Crystal structure of Mycobacterium tuberculosis EspR in complex with a small DNA fragment

PDB ID 3qyx

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