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3r7g
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 3r7g is ON HOLD Authors: Kreutz, B., Vizcarra, C.L., Rodal, A.A., Toms, A.V., Lu, Jun, Zeth, Z., Kerkhoff, E., Quinlan, M.E., Eck, M.J. Description...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of Spire KIND domain in complex with the tail of FMN2== | |
| - | + | <StructureSection load='3r7g' size='340' side='right'caption='[[3r7g]], [[Resolution|resolution]] 2.20Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[3r7g]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3R7G OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3R7G FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2Å</td></tr> | |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3r7g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3r7g OCA], [https://pdbe.org/3r7g PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3r7g RCSB], [https://www.ebi.ac.uk/pdbsum/3r7g PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3r7g ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/SPIR1_HUMAN SPIR1_HUMAN] Acts as a actin nucleation factor, remains associated with the slow-growing pointed end of the new filament. Involved in intracellular vesicle transport along actin fibers, providing a novel link between actin cytoskeleton dynamics and intracellular transport. Required for asymmetric spindle positioning and asymmetric cell division during meiosis. Required for normal formation of the cleavage furrow and for polar body extrusion during female germ cell meiosis.<ref>PMID:11747823</ref> <ref>PMID:21620703</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Eck MJ]] | ||
| + | [[Category: Kreutz B]] | ||
| + | [[Category: Lu J]] | ||
| + | [[Category: Quinlan ME]] | ||
| + | [[Category: Rodal AA]] | ||
| + | [[Category: Toms AV]] | ||
| + | [[Category: Vizcarra CL]] | ||
Current revision
Crystal structure of Spire KIND domain in complex with the tail of FMN2
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Categories: Homo sapiens | Large Structures | Eck MJ | Kreutz B | Lu J | Quinlan ME | Rodal AA | Toms AV | Vizcarra CL
