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8ohz
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 8ohz is ON HOLD Authors: Morstein, J., Amatuni, A., Schuster, A., Kuttenlochner, W., Ko, T., Groll, M., Adibekian, A., Renata, H., Trauner, D.H. De...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Yeast 20S proteasome in complex with a photoswitchable cepafungin derivative (transCep1)== | |
| - | + | <StructureSection load='8ohz' size='340' side='right'caption='[[8ohz]], [[Resolution|resolution]] 2.65Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8ohz]] is a 20 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8OHZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8OHZ FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.65Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=VOT:(2~{S},3~{R})-2-[2-[4-[2-(4-ethylphenyl)hydrazinyl]phenyl]ethanoylamino]-~{N}-[(5~{S},8~{S},10~{S})-5-methyl-10-oxidanyl-2,7-bis(oxidanylidene)-1,6-diazacyclododec-8-yl]-3-oxidanyl-butanamide'>VOT</scene></td></tr> |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8ohz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8ohz OCA], [https://pdbe.org/8ohz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8ohz RCSB], [https://www.ebi.ac.uk/pdbsum/8ohz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8ohz ProSAT]</span></td></tr> |
| - | [[Category: | + | </table> |
| - | [[Category: | + | == Function == |
| - | [[Category: | + | [https://www.uniprot.org/uniprot/PSA2_YEAST PSA2_YEAST] The proteasome degrades poly-ubiquitinated proteins in the cytoplasm and in the nucleus. It is essential for the regulated turnover of proteins and for the removal of misfolded proteins. The proteasome is a multicatalytic proteinase complex that is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. It has an ATP-dependent proteolytic activity. |
| - | [[Category: | + | __TOC__ |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Saccharomyces cerevisiae]] |
| - | [[Category: Schuster | + | [[Category: Adibekian A]] |
| + | [[Category: Amatuni A]] | ||
| + | [[Category: Groll M]] | ||
| + | [[Category: Ko T]] | ||
| + | [[Category: Kuttenlochner W]] | ||
| + | [[Category: Morstein J]] | ||
| + | [[Category: Renata H]] | ||
| + | [[Category: Schuster A]] | ||
| + | [[Category: Trauner DH]] | ||
Current revision
Yeast 20S proteasome in complex with a photoswitchable cepafungin derivative (transCep1)
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