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8ptq
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==COMPLEX CRYSTAL STRUCTURE OF MUTANT HUMAN MONOGLYCERIDE LIPASE WITH COMPOUND 5l== | |
| - | + | <StructureSection load='8ptq' size='340' side='right'caption='[[8ptq]], [[Resolution|resolution]] 1.55Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8ptq]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8PTQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8PTQ FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.55Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=EJI:methyl+4-[(2~{S},3~{R})-3-(4-fluorophenyl)-1-(1-methanoylpiperidin-4-yl)-4-oxidanylidene-azetidin-2-yl]benzoate'>EJI</scene></td></tr> |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8ptq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8ptq OCA], [https://pdbe.org/8ptq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8ptq RCSB], [https://www.ebi.ac.uk/pdbsum/8ptq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8ptq ProSAT]</span></td></tr> |
| - | [[Category: | + | </table> |
| - | [[Category: | + | == Function == |
| - | [[Category: | + | [https://www.uniprot.org/uniprot/MGLL_HUMAN MGLL_HUMAN] Converts monoacylglycerides to free fatty acids and glycerol. Hydrolyzes the endocannabinoid 2-arachidonoylglycerol, and thereby contributes to the regulation of endocannabinoid signaling, nociperception and perception of pain (By similarity). Regulates the levels of fatty acids that serve as signaling molecules and promote cancer cell migration, invasion and tumor growth.<ref>PMID:20079333</ref> |
| - | [[Category: | + | == References == |
| - | [[Category: | + | <references/> |
| - | [[Category: | + | __TOC__ |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: | + | [[Category: Homo sapiens]] |
| - | [[Category: Grillo | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Benz J]] |
| - | [[Category: Leibrock | + | [[Category: Butini S]] |
| - | [[Category: | + | [[Category: Campiani G]] |
| + | [[Category: Carullo G]] | ||
| + | [[Category: Di Guglielmo B]] | ||
| + | [[Category: Federico S]] | ||
| + | [[Category: Gemma S]] | ||
| + | [[Category: Grether U]] | ||
| + | [[Category: Grillo A]] | ||
| + | [[Category: Lamponi S]] | ||
| + | [[Category: Leibrock L]] | ||
| + | [[Category: Maramai S]] | ||
| + | [[Category: Papa A]] | ||
Current revision
COMPLEX CRYSTAL STRUCTURE OF MUTANT HUMAN MONOGLYCERIDE LIPASE WITH COMPOUND 5l
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Categories: Homo sapiens | Large Structures | Benz J | Butini S | Campiani G | Carullo G | Di Guglielmo B | Federico S | Gemma S | Grether U | Grillo A | Lamponi S | Leibrock L | Maramai S | Papa A
