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3okw

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'''Unreleased structure'''
 
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The entry 3okw is ON HOLD until Paper Publication
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==Mouse Semaphorin 6A, extracellular domains 1-2==
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<StructureSection load='3okw' size='340' side='right'caption='[[3okw]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3okw]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OKW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3OKW FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.299&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3okw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3okw OCA], [https://pdbe.org/3okw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3okw RCSB], [https://www.ebi.ac.uk/pdbsum/3okw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3okw ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/SEM6A_MOUSE SEM6A_MOUSE] Cell surface receptor for PLXNA2 that plays an important role in cell-cell signaling. Required for normal granule cell migration in the developing cerebellum. Promotes reorganization of the actin cytoskeleton and plays an important role in axon guidance in the developing central nervous system. Can act as repulsive axon guidance cue. Has repulsive action towards migrating granular neurons. May play a role in channeling sympathetic axons into the sympathetic chains and controlling the temporal sequence of sympathetic target innervation.<ref>PMID:16205717</ref> <ref>PMID:19063725</ref> <ref>PMID:20877282</ref> <ref>PMID:20881961</ref>
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Authors: Janssen, B.J.C., Robinson, R.A., Bell, C.H., Siebold, C., Jones, E.Y.
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==See Also==
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*[[Semaphorin 3D structures|Semaphorin 3D structures]]
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Description: Mouse Semaphorin 6A, extracellular domains 1-2
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== References ==
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<references/>
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 29 07:56:25 2010''
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Mus musculus]]
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[[Category: Bell CH]]
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[[Category: Janssen BJC]]
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[[Category: Jones EY]]
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[[Category: Robinson RA]]
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[[Category: Siebold C]]

Current revision

Mouse Semaphorin 6A, extracellular domains 1-2

PDB ID 3okw

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