This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


3okw

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (11:17, 21 February 2024) (edit) (undo)
 
(4 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:3okw.png|left|200px]]
 
-
{{STRUCTURE_3okw| PDB=3okw | SCENE= }}
+
==Mouse Semaphorin 6A, extracellular domains 1-2==
-
 
+
<StructureSection load='3okw' size='340' side='right'caption='[[3okw]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
-
===Mouse Semaphorin 6A, extracellular domains 1-2===
+
== Structural highlights ==
-
 
+
<table><tr><td colspan='2'>[[3okw]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OKW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3OKW FirstGlance]. <br>
-
{{ABSTRACT_PUBMED_20877282}}
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.299&#8491;</td></tr>
-
 
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
-
==About this Structure==
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3okw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3okw OCA], [https://pdbe.org/3okw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3okw RCSB], [https://www.ebi.ac.uk/pdbsum/3okw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3okw ProSAT]</span></td></tr>
-
[[3okw]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OKW OCA].
+
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/SEM6A_MOUSE SEM6A_MOUSE] Cell surface receptor for PLXNA2 that plays an important role in cell-cell signaling. Required for normal granule cell migration in the developing cerebellum. Promotes reorganization of the actin cytoskeleton and plays an important role in axon guidance in the developing central nervous system. Can act as repulsive axon guidance cue. Has repulsive action towards migrating granular neurons. May play a role in channeling sympathetic axons into the sympathetic chains and controlling the temporal sequence of sympathetic target innervation.<ref>PMID:16205717</ref> <ref>PMID:19063725</ref> <ref>PMID:20877282</ref> <ref>PMID:20881961</ref>
==See Also==
==See Also==
-
*[[Semaphorin|Semaphorin]]
+
*[[Semaphorin 3D structures|Semaphorin 3D structures]]
-
 
+
== References ==
-
==Reference==
+
<references/>
-
<ref group="xtra">PMID:020877282</ref><references group="xtra"/>
+
__TOC__
 +
</StructureSection>
 +
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
-
[[Category: Bell, C H.]]
+
[[Category: Bell CH]]
-
[[Category: Janssen, B J.C.]]
+
[[Category: Janssen BJC]]
-
[[Category: Jones, E Y.]]
+
[[Category: Jones EY]]
-
[[Category: Robinson, R A.]]
+
[[Category: Robinson RA]]
-
[[Category: Siebold, C.]]
+
[[Category: Siebold C]]
-
[[Category: Cell-cell signalling]]
+
-
[[Category: Ligand]]
+
-
[[Category: Plexin a2]]
+
-
[[Category: Sema-domain]]
+
-
[[Category: Signaling protein]]
+
-
[[Category: Transmembrane]]
+

Current revision

Mouse Semaphorin 6A, extracellular domains 1-2

PDB ID 3okw

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/3okw"
Personal tools