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3op8

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{{STRUCTURE_3op8| PDB=3op8 | SCENE= }}
 
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===Crystal structure of the domain V from beta2-glycoprotein I===
 
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{{ABSTRACT_PUBMED_21179511}}
 
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==Function==
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==Crystal structure of the domain V from beta2-glycoprotein I==
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[[http://www.uniprot.org/uniprot/APOH_HUMAN APOH_HUMAN]] Binds to various kinds of negatively charged substances such as heparin, phospholipids, and dextran sulfate. May prevent activation of the intrinsic blood coagulation cascade by binding to phospholipids on the surface of damaged cells.
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<StructureSection load='3op8' size='340' side='right'caption='[[3op8]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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== Structural highlights ==
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==About this Structure==
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<table><tr><td colspan='2'>[[3op8]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OP8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3OP8 FirstGlance]. <br>
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[[3op8]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OP8 OCA].
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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==Reference==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3op8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3op8 OCA], [https://pdbe.org/3op8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3op8 RCSB], [https://www.ebi.ac.uk/pdbsum/3op8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3op8 ProSAT]</span></td></tr>
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<ref group="xtra">PMID:021179511</ref><references group="xtra"/><references/>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/APOH_HUMAN APOH_HUMAN] Binds to various kinds of negatively charged substances such as heparin, phospholipids, and dextran sulfate. May prevent activation of the intrinsic blood coagulation cascade by binding to phospholipids on the surface of damaged cells.
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__TOC__
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Beglova, N.]]
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[[Category: Large Structures]]
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[[Category: Biasio, A De.]]
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[[Category: Beglova N]]
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[[Category: Kolyada, A.]]
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[[Category: De Biasio A]]
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[[Category: Lee, C J.]]
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[[Category: Kolyada A]]
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[[Category: Anionic phospholipids binding]]
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[[Category: Lee C-J]]
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[[Category: Antiphospholipid syndrome]]
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[[Category: Blood plasma]]
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[[Category: Lipoprotein receptors binding]]
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[[Category: Protein binding]]
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[[Category: Sushi]]
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Current revision

Crystal structure of the domain V from beta2-glycoprotein I

PDB ID 3op8

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