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3D structures of ubiquitin
From Proteopedia
(Difference between revisions)
(New page: == 3D Structures of Ubiquitin == Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} - For a general description of the protein see Ubiquitin {{#tree:id=Organ...) |
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**[[2ojr]], [[2nr2]], [[2fcq]], [[1ubi]], [[1ubq]], [[1xqq]], [[3ons]], [[4wzp]], [[5k9p]], [[4zqs]], [[5dk8]], [[4xof]], [[4xok]], [[4xol]], [[4zpz]] - hUBB - human<br /> | **[[2ojr]], [[2nr2]], [[2fcq]], [[1ubi]], [[1ubq]], [[1xqq]], [[3ons]], [[4wzp]], [[5k9p]], [[4zqs]], [[5dk8]], [[4xof]], [[4xok]], [[4xol]], [[4zpz]] - hUBB - human<br /> | ||
| - | **[[2zcb]], [[2gbj]], [[2gbk]], [[2gbm]], [[2gbn]], [[2gbr]], [[2fcm]], [[2fcn]], [[2fcs]], [[1yiw]], [[1yj1]], [[1sif]], [[1ogw]], [[4hk2]], [[4hjk]], [[4pij]], [[4pih]], [[4pig]] - hUBB (mutant)<br /> | + | **[[2zcb]], [[2gbj]], [[2gbk]], [[2gbm]], [[2gbn]], [[2gbr]], [[2fcm]], [[2fcn]], [[2fcs]], [[1yiw]], [[1yj1]], [[1sif]], [[1ogw]], [[4hk2]], [[4hjk]], [[4pij]], [[4pih]], [[4pig]], [[7ooj]] - hUBB (mutant)<br /> |
**[[2kn5]], [[2klg]], [[2jzz]], [[2pe9]], [[2pea]], [[1g6j]], [[1d3z]], [[2kox]], [[2ld9]], [[2k25]], [[5ujl]], [[6v5d]] – hUBB – NMR<br /> | **[[2kn5]], [[2klg]], [[2jzz]], [[2pe9]], [[2pea]], [[1g6j]], [[1d3z]], [[2kox]], [[2ld9]], [[2k25]], [[5ujl]], [[6v5d]] – hUBB – NMR<br /> | ||
**[[1c3t]], [[1ud7]], [[2mi8]], [[2rsu]], [[2ru6]], [[6k4i]], [[5zd0]] - hUBB (mutant) - NMR<br /> | **[[1c3t]], [[1ud7]], [[2mi8]], [[2rsu]], [[2ru6]], [[6k4i]], [[5zd0]] - hUBB (mutant) - NMR<br /> | ||
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* Ubiquitin dimer | * Ubiquitin dimer | ||
| - | **[[2xk5]], [[3nob]], [[2xew]], [[3h7p]], [[3h7s]], [[2w9n]], [[2jf5]], [[3ns8]], [[3aul]], [[3axc]], [[5gob]], [[5goc]], [[5god]], [[5gog]], [[5goh]], [[5goi]], [[5goj]], [[5j8p]] – hDiUBB<br /> | + | **[[2xk5]], [[3nob]], [[2xew]], [[3h7p]], [[3h7s]], [[2w9n]], [[2jf5]], [[3ns8]], [[3aul]], [[3axc]], [[5gob]], [[5goc]], [[5god]], [[5gog]], [[5goh]], [[5goi]], [[5goj]], [[5j8p]], [[7s6o]] – hDiUBB<br /> |
| + | **[[5emz]], [[5khy]], [[8ic9]] – hDiUBB (mutant)<br /> | ||
**[[2mbo]], [[2mbq]] – hDiUBB – NMR<br /> | **[[2mbo]], [[2mbq]] – hDiUBB – NMR<br /> | ||
**[[2bgf]] – hDiUBB – chemical relaxation<br /> | **[[2bgf]] – hDiUBB – chemical relaxation<br /> | ||
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**[[4hxd]] – hDiUBB + RNA polymerase <br /> | **[[4hxd]] – hDiUBB + RNA polymerase <br /> | ||
**[[5o6t]] – hDiUBB + E3 UBB protein ligase XIAP<br /> | **[[5o6t]] – hDiUBB + E3 UBB protein ligase XIAP<br /> | ||
| + | **[[7m4m]], [[7m4n]], [[7m4o]] – hDiUBB + E3 UBB protein ligase RNF216<br /> | ||
**[[2lvp]], [[2lvq]] – hDiUBB + E3 UBB protein ligase - NMR<br /> | **[[2lvp]], [[2lvq]] – hDiUBB + E3 UBB protein ligase - NMR<br /> | ||
**[[4ksk]], [[4ksl]] – hDiUBB + Fam105B<br /> | **[[4ksk]], [[4ksl]] – hDiUBB + Fam105B<br /> | ||
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**[[3wwq]] – hDiUBB + FAAP20 peptide <br /> | **[[3wwq]] – hDiUBB + FAAP20 peptide <br /> | ||
**[[5ohp]], [[5ohn]], [[5ohk]] – hDiUBB + USP30<br /> | **[[5ohp]], [[5ohn]], [[5ohk]] – hDiUBB + USP30<br /> | ||
| + | **[[7keo]] – hDiUBB + antigen binding fragment <br /> | ||
| + | **[[7eal]] – hDiUBB + ABIN-1 <br /> | ||
| + | **[[7uyh]] – hDiUBB + LOTA <br /> | ||
| + | **[[7uv5]] – hDiUBB+ papain-like protease<br /> | ||
**[[3ptf]], [[6if1]] – hDiUBB + UBB conjugating enzyme E2<br /> | **[[3ptf]], [[6if1]] – hDiUBB + UBB conjugating enzyme E2<br /> | ||
**[[3a1q]] – mDiUBB+UBB interaction motif-containing protein <br /> | **[[3a1q]] – mDiUBB+UBB interaction motif-containing protein <br /> | ||
**[[2znv]] – mDiUBB+hAMSH-like protease<br /> | **[[2znv]] – mDiUBB+hAMSH-like protease<br /> | ||
| + | **[[7e62]] – mDiUBB (mutant) + TAB-2 <br /> | ||
**[[2kde]], [[2kdf]] – fDiUBB+26S proteasome non-ATPase regulatory subunit - NMR<br /> | **[[2kde]], [[2kdf]] – fDiUBB+26S proteasome non-ATPase regulatory subunit - NMR<br /> | ||
**[[6jwi]] – yDiUBB + Npl4<br /> | **[[6jwi]] – yDiUBB + Npl4<br /> | ||
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**[[4boz]] – hTriUBB + UBB thiolesterase <br /> | **[[4boz]] – hTriUBB + UBB thiolesterase <br /> | ||
**[[3vuw]], [[3vux]] – hTriUBB + TNF α-induced proitein <br /> | **[[3vuw]], [[3vux]] – hTriUBB + TNF α-induced proitein <br /> | ||
| + | **[[8f1f]] – hTriUBB + non-proteinogenic cyclic peptide<br /> | ||
| + | **[[7nbb]], [[8a67]] – hTriUBB + nanobody<br /> | ||
| + | **[[7eao]] – hTriUBB + ABIN-1<br /> | ||
* Ubiquitin tetramer | * Ubiquitin tetramer | ||
| - | **[[5go8]], [[5xdp]] – hTetraUBB <br /> | + | **[[1f9j]], [[1tbe]] [[2o6v]], [[3alb]], [[3hm3]], [[5go8]], [[5xdp]] – hTetraUBB <br /> |
| + | **[[8e7o]] – hTetraUBB (mutant) <br /> | ||
**[[3tmp]] – hTetraUBB + deubiquitinase<br /> | **[[3tmp]] – hTetraUBB + deubiquitinase<br /> | ||
| - | **[[3alb]], [[3hm3]], [[2o6v]], [[1f9j]], [[1tbe]] – tetra-hUBB<br /> | ||
**[[3zni]] – hTetraUBB + E3 UBB protein ligase + tyrosine protein kinase + UBB conjugating enzyme E2<br /> | **[[3zni]] – hTetraUBB + E3 UBB protein ligase + tyrosine protein kinase + UBB conjugating enzyme E2<br /> | ||
**[[5b83]] – hTetraUBB + optineurin<br /> | **[[5b83]] – hTetraUBB + optineurin<br /> | ||
**[[3vuy]] – hTetraUBB + TNF α-induced proitein <br /> | **[[3vuy]] – hTetraUBB + TNF α-induced proitein <br /> | ||
| + | **[[7eb9]] – hTetraUBB + ABIN-1<br /> | ||
| + | **[[7yui]] – hTetraUBB + HOIL-1<br /> | ||
* Polyubiquitin-B | * Polyubiquitin-B | ||
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**[[5vey]] – hUBB + RNF169 + Histone H2A-H2B - NMR<br /> | **[[5vey]] – hUBB + RNF169 + Histone H2A-H2B - NMR<br /> | ||
**[[5n38]] , [[5n2w]], [[6glc]] – hUBB + E3 UBB protein ligase PARKIN<br /> | **[[5n38]] , [[5n2w]], [[6glc]] – hUBB + E3 UBB protein ligase PARKIN<br /> | ||
| + | **[[8c07]] – hUBB + E3 UBB protein ligase UBR5 – Cryo EM<br /> | ||
| + | **[[7ojx]] – hUBB + E3 + E2<br /> | ||
**[[6fyh]] – hUBB + E3 UBB protein ligase HUWE1<br /> | **[[6fyh]] – hUBB + E3 UBB protein ligase HUWE1<br /> | ||
**[[6fx4]] – hUBB (mutant) + E3 UBB protein ligase SMURF2<br /> | **[[6fx4]] – hUBB (mutant) + E3 UBB protein ligase SMURF2<br /> | ||
**[[6hek]] – hUBB + USP<br /> | **[[6hek]] – hUBB + USP<br /> | ||
**[[5mnj]] – hUBB + E3 UBB protein ligase MDM2 + UbcH5B<br /> | **[[5mnj]] – hUBB + E3 UBB protein ligase MDM2 + UbcH5B<br /> | ||
| + | **[[7ay2]] – hUBB + WD repeat-containing protein 48 + USP1<br /> | ||
**[[6hpr]] – hUBB + IAP1 + UbcH5B<br /> | **[[6hpr]] – hUBB + IAP1 + UbcH5B<br /> | ||
**[[6njg]] – hUBB + vacuolar protein sorting-associated protein 27<br /> | **[[6njg]] – hUBB + vacuolar protein sorting-associated protein 27<br /> | ||
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**[[6a6i]] – hUBB + Cockayne syndrome group B protein <br /> | **[[6a6i]] – hUBB + Cockayne syndrome group B protein <br /> | ||
**[[5wvo]] – hUBB + hUBC + UCLH3<br /> | **[[5wvo]] – hUBB + hUBC + UCLH3<br /> | ||
| + | **[[7w3u]] – hUBB + UBB carboxy terminal hydrolase 34<br /> | ||
| + | **[[8bs9]] – hUBB + UBB carboxy terminal hydrolase 36<br /> | ||
| + | **[[7ne8]], [[8h1t]], [[8sn0]], [[8sn3]], [[8sn4]], [[8sn5]], [[8sn6]], [[8sn7]], [[8sn8]], [[8sn9]], [[8sna]], [[8txv]], [[8txw]], [[8txx]], [[8wg5]] – hUBB in nucleosome – Cryo EM<br /> | ||
| + | **[[7f7x]] – hUBB + ubiquitin-2 - NMR<br /> | ||
| + | **[[8cmr]] – hUBB + OUT domain--containing protein<br /> | ||
| + | **[[7oje]] – hUBB + deubiquitinase<br /> | ||
| + | **[[6xz1]] – hUBB + HUWE1<br /> | ||
* Polyubiquitin-C | * Polyubiquitin-C | ||
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**[[6ypt]] – hUBC + RNA replicase<br /> | **[[6ypt]] – hUBC + RNA replicase<br /> | ||
**[[6tnf]] – hUBC + FANCI + FANCD2 + DNA - Cryo EM<br /> | **[[6tnf]] – hUBC + FANCI + FANCD2 + DNA - Cryo EM<br /> | ||
| + | **[[7b5n]] – hUBC + Cul1 + Nedd8 + RBX1 + ARITH1 + Ube2L3 – Cryo EM<br /> | ||
| + | **[[7b5l]], [[7b5m]] – hUBC in SCF-RBR E3-E2 complex – Cryo EM<br /> | ||
| + | **[[8b3i]] – hUBC in CRl4CSA E2 complex – Cryo EM<br /> | ||
| + | **[[6z7v]] – hUBC + Mindy-2<br /> | ||
| + | **[[7npi]] – hPentaUBC + Mindy-2<br /> | ||
| + | **[[7tv4]] – hUBC + NEMO + RNF31 peptide<br /> | ||
| + | **[[7lmz]], [[7ln0]], [[7ln1]] – hHexaUBC + p97 – Cryo EM<br /> | ||
| + | **[[7owd]] – hUBC in UBC8/UBE2H-GID/CTLH complex – Cryo EM<br /> | ||
| - | * Ubiquitin monomer bound to protein | + | * Ubiquitin monomer bound to a single protein |
**[[3ofi]] – hUBB+insulin protease | **[[3ofi]] – hUBB+insulin protease | ||
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**[[3rul]] – hUBB + dalvancin<br /> | **[[3rul]] – hUBB + dalvancin<br /> | ||
**[[3vfk]] – hUBB + monodechloro-teicoplanin <br /> | **[[3vfk]] – hUBB + monodechloro-teicoplanin <br /> | ||
| - | **[[4ium]], [[4wur]], [[4mm3]] – hUBB+ papain-like protease<br /> | + | **[[4ium]], [[4wur]], [[4mm3]], [[7f0u]], [[7mc9]], [[7rbr]], [[8cx9]], [[8eho]] – hUBB+ papain-like protease<br /> |
**[[2lz6]], [[2mcn]] – hUBB + CD2-associated protein<br /> | **[[2lz6]], [[2mcn]] – hUBB + CD2-associated protein<br /> | ||
**[[2mbh]] – hUBB + Kreuppel-like factor<br /> | **[[2mbh]] – hUBB + Kreuppel-like factor<br /> | ||
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**[[5lrw]] – hUBB (mutant)+ OTU domain containing protein 7B<br /> | **[[5lrw]] – hUBB (mutant)+ OTU domain containing protein 7B<br /> | ||
**[[5lrx]] – hUBB (mutant)+ OTU domain containing protein 7C<br /> | **[[5lrx]] – hUBB (mutant)+ OTU domain containing protein 7C<br /> | ||
| - | **[[5kgf]] – hUBB + nucleosome - Cryo EM<br /> | ||
**[[2nbv]] – hUBB + proteasomal UBB receptor - NMR<br /> | **[[2nbv]] – hUBB + proteasomal UBB receptor - NMR<br /> | ||
**[[5jg6]] – hUBB + anaphase promoting complex subunit 11<br /> | **[[5jg6]] – hUBB + anaphase promoting complex subunit 11<br /> | ||
| - | **[[6eqi]] – hUBB + NB696 + PINK1<br /> | ||
**[[5ohv]] – hUBB + K33-specific affimer<br /> | **[[5ohv]] – hUBB + K33-specific affimer<br /> | ||
**[[4un2]] – hUBB + Dsk2 peptide<br /> | **[[4un2]] – hUBB + Dsk2 peptide<br /> | ||
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**[[6upu]] – hUBB + otDUB<br /> | **[[6upu]] – hUBB + otDUB<br /> | ||
**[[6pgv]] – hUBB + Josephine 2<br /> | **[[6pgv]] – hUBB + Josephine 2<br /> | ||
| + | **[[8dmq]], [[8dms]] – hUBB + MAVL<br /> | ||
| + | **[[8efx]] – hUBB + OtDUB<br /> | ||
| + | **[[7jxv]] – hUBB + CALM<br /> | ||
| + | **[[7mic]] – hUBB + RNA replication protein<br /> | ||
| + | **[[8ivb]] – hUBB + Bcl2-L-7 - NMR<br /> | ||
| + | **[[8htd]], [[8hte]], [[8htf]] – hUBB + ADP-ribosyltransferase<br /> | ||
| + | **[[8efw]] – hUBB (mutant) + SDEA<br /> | ||
| + | **[[7rma]] – hUBB (mutant) + ANKRD13D<br /> | ||
**[[4m0w]] – bUBB + replicase polyprotein<br /> | **[[4m0w]] – bUBB + replicase polyprotein<br /> | ||
**[[1uzx]] – bUBB+VPS23 UEV<br /> | **[[1uzx]] – bUBB+VPS23 UEV<br /> | ||
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**[[2l00]] – yUBB + Zfand5<br /> | **[[2l00]] – yUBB + Zfand5<br /> | ||
| - | * Ubiquitin | + | *Ubiquitin bound to multi proteins |
| - | **[[5l8w]], [[5cvn]], [[5cvo]] – hUBB + | + | **[[5l8w]], [[5cvn]], [[5cvo]] – hUBB + UBB carboxy terminal hydrolase 12 + WD repeat containing protein 48<br /> |
| + | **[[1yx5]], [[1yx6]] - hUBB+26S proteasome non-ATPase regulatory subunit – NMR<br /> | ||
**[[4dhj]], [[4dhz]] – hUBB (mutant) + UBB thiolesterase + UBB aldehyde <br /> | **[[4dhj]], [[4dhz]] – hUBB (mutant) + UBB thiolesterase + UBB aldehyde <br /> | ||
| - | **[[ | + | **[[5v1z]], [[5v1y]] – hUBB + RPN13 + RPN2<br /> |
| - | **[[ | + | **[[5kgf]], [[7bwd]], [[7k6q]], [[7lyc]], [[7xcr]], [[8grm]], [[8svf]] – hUBB in nucleosome – Cryo EM<br /> |
| - | + | **[[7k6p]] – hUBB (mutant) in nucleosome – Cryo EM<br /> | |
| - | + | **[[6eqi]] – hUBB + NB696 + PINK1<br /> | |
| - | + | **[[7dni]], [[7dnj]] – hUBB + MAVS + CARDS – Cryo EM<br /> | |
| - | **[[ | + | **[[8dar]], [[8das]], [[8dat]], [[8dau]], [[8dav]], [[8daw]] – yUBB in UFD1/NPL4/CDC48 complex– Cryo EM<br /> |
| - | **[[ | + | **[[8c83]] – yUBB + OTU2 + 40S ribosome– Cryo EM<br /> |
| - | **[[ | + | |
| - | **[[ | + | |
| - | + | ||
| - | **[[ | + | |
* Ubiquitin complex with ubiquitination enzymes | * Ubiquitin complex with ubiquitination enzymes | ||
| - | **[[1fxt]], [[3oj4]], [[3ugb]], [[5dfl]], [[3k9p]], [[3a33]], [[5ulf]], [[5tut]], [[6nyo]], [[6jb6]], [[6jb7]] – hUBB + UBB conjugating enzyme E2<br /> | + | **[[1fxt]], [[3oj4]], [[3ugb]], [[5dfl]], [[3k9p]], [[3a33]], [[5ulf]], [[5tut]], [[6nyo]], [[6jb6]], [[6jb7]], [[7m2k]] – hUBB + UBB conjugating enzyme E2<br /> |
| - | **[[5bnb]], [[2kjh]], [[1zgu]], [[6d4p]], [[6d6i]] – hUBB (mutant) + UBB conjugating enzyme E2<br /> | + | **[[5bnb]], [[2kjh]], [[1zgu]], [[6d4p]], [[6d6i]], [[7myf]], [[7myh]] – hUBB (mutant) + UBB conjugating enzyme E2<br /> |
| - | **[[5edv]], [[4whv]], [[5ait]], [[5aiu]], [[3jvz]], [[3jw0]], [[5udh]], [[5tte]], [[6w9d]] – hUBB + UBB conjugating enzyme E2 + E3 UBB-protein ligase<br /> | + | **[[8st7]], [[8st8]], [[8st9]] – hUBB + E3 UBB-protein ligase SOPA<br /> |
| + | **[[7m3q]] – hUBB (mutant) + E3 UBB-protein ligase Smurf2<br /> | ||
| + | **[[7us1]] – hUBB (mutant) + E3 UBB-protein ligase Parkin<br /> | ||
| + | **[[5edv]], [[4whv]], [[5ait]], [[5aiu]], [[3jvz]], [[3jw0]], [[5udh]], [[5tte]], [[6w9d]], [[6w9d]], [[7bbd]], [[7bbf]], [[7r71]] – hUBB + UBB conjugating enzyme E2 + E3 UBB-protein ligase<br /> | ||
| + | **[[8eb0]] – hUBB + E3 UBB protein ligase RNF216 + UBB conjugating enzyme E2<br /> | ||
| + | **[[8ams]], [[8pjn]] – hPolyUBB-C + UBB conjugating enzyme E2 + E3 UBB-protein ligase<br /> | ||
| + | **[[8pql]] – hPolyUBB-C + UBB conjugating enzyme E2 R2 + E3 UBB-protein ligase RBX1 + cullin-2 + elongin –B + elongin-C + FEM1C – Cryo EM<br /> | ||
| + | **[[6ulh]], [[6ump]], [[6ums], [[7bxg]]] – hUBB (mutant) + UBB conjugating enzyme E2 + MavC<br /> | ||
| + | **[[7mex]], [[7mey]] – hUBB + UBB conjugating enzyme E2 + E3 UBB-protein ligase + degron – Cryo EM<br /> | ||
| + | **[7k5jl]] – UBB (mutant) + yUBB activating enzyme E1 + yUBB conjugating enzyme E2 - wheat<br /> | ||
**[[2gmi]] – hUBB + UBB conjugating enzyme E2<br /> | **[[2gmi]] – hUBB + UBB conjugating enzyme E2<br /> | ||
**[[2fuh]] – hUBB + UBB conjugating enzyme E2 - NMR<br /> | **[[2fuh]] – hUBB + UBB conjugating enzyme E2 - NMR<br /> | ||
Current revision
3D Structures of Ubiquitin
Updated on 22-February-2024 - For a general description of the protein see Ubiquitin
