This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
3rhz
From Proteopedia
(Difference between revisions)
| (4 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | [[Image:3rhz.png|left|200px]] | ||
| - | + | ==Structure and functional analysis of a new subfamily of glycosyltransferases required for glycosylation of serine-rich streptococcal adhesions== | |
| - | + | <StructureSection load='3rhz' size='340' side='right'caption='[[3rhz]], [[Resolution|resolution]] 1.90Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[3rhz]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_parasanguinis Streptococcus parasanguinis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RHZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3RHZ FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.898Å</td></tr> | |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=UDP:URIDINE-5-DIPHOSPHATE'>UDP</scene></td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3rhz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rhz OCA], [https://pdbe.org/3rhz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3rhz RCSB], [https://www.ebi.ac.uk/pdbsum/3rhz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3rhz ProSAT]</span></td></tr> | |
| - | + | </table> | |
| - | + | == Function == | |
| - | + | [https://www.uniprot.org/uniprot/GTF3_STRPA GTF3_STRPA] Required for polymorphic O-glycosylation of the serine-rich repeat protein Fap1. Catalyzes the second step in glycosylation of the serine-rich repeat protein in this bacteria. Transfers glucose from UDP-glucose to the terminal GlcNAc moiety of 3-O-(N-acetyl-alpha-D-glucosaminyl)-L-seryl-[protein] which results from the first glycosylation step of Fap1; does not use other sugar nucleotides as substrates.<ref>PMID:20164186</ref> <ref>PMID:21653318</ref> <ref>PMID:25404702</ref> | |
| - | + | == References == | |
| - | < | + | <references/> |
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
| - | + | [[Category: Large Structures]] | |
| - | + | ||
| - | + | ||
| - | == | + | |
| - | [[3rhz]] is a 2 chain structure with sequence from [ | + | |
| - | + | ||
| - | == | + | |
| - | < | + | |
[[Category: Streptococcus parasanguinis]] | [[Category: Streptococcus parasanguinis]] | ||
| - | [[Category: Li | + | [[Category: Li J]] |
| - | [[Category: Wu | + | [[Category: Wu H]] |
| - | [[Category: Zhu | + | [[Category: Zhu F]] |
| - | + | ||
| - | + | ||
Current revision
Structure and functional analysis of a new subfamily of glycosyltransferases required for glycosylation of serine-rich streptococcal adhesions
| |||||||||||
