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3s5n
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 3s5n is ON HOLD Authors: Riedel, T.J., Lowther, W.T. Description: Crystal Structure of Human 4-hydroxy-2-oxoglutarate Aldolase) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal Structure of Human 4-hydroxy-2-oxoglutarate Aldolase== | |
| + | <StructureSection load='3s5n' size='340' side='right'caption='[[3s5n]], [[Resolution|resolution]] 2.50Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[3s5n]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3S5N OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3S5N FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3s5n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3s5n OCA], [https://pdbe.org/3s5n PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3s5n RCSB], [https://www.ebi.ac.uk/pdbsum/3s5n PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3s5n ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Disease == | ||
| + | [https://www.uniprot.org/uniprot/HOGA1_HUMAN HOGA1_HUMAN] Primary hyperoxaluria type 3. The disease is caused by mutations affecting the gene represented in this entry. | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/HOGA1_HUMAN HOGA1_HUMAN] Catalyzes the final step in the metabolic pathway of hydroxyproline.<ref>PMID:20797690</ref> <ref>PMID:21998747</ref> | ||
| - | + | ==See Also== | |
| - | + | *[[Aldolase 3D structures|Aldolase 3D structures]] | |
| - | + | == References == | |
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Lowther WT]] | ||
| + | [[Category: Riedel TJ]] | ||
Current revision
Crystal Structure of Human 4-hydroxy-2-oxoglutarate Aldolase
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