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3s5n

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[[Image:3s5n.png|left|200px]]
 
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==Crystal Structure of Human 4-hydroxy-2-oxoglutarate Aldolase==
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The line below this paragraph, containing "STRUCTURE_3s5n", creates the "Structure Box" on the page.
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<StructureSection load='3s5n' size='340' side='right'caption='[[3s5n]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3s5n]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3S5N OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3S5N FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
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{{STRUCTURE_3s5n| PDB=3s5n | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3s5n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3s5n OCA], [https://pdbe.org/3s5n PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3s5n RCSB], [https://www.ebi.ac.uk/pdbsum/3s5n PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3s5n ProSAT]</span></td></tr>
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</table>
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== Disease ==
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[https://www.uniprot.org/uniprot/HOGA1_HUMAN HOGA1_HUMAN] Primary hyperoxaluria type 3. The disease is caused by mutations affecting the gene represented in this entry.
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== Function ==
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[https://www.uniprot.org/uniprot/HOGA1_HUMAN HOGA1_HUMAN] Catalyzes the final step in the metabolic pathway of hydroxyproline.<ref>PMID:20797690</ref> <ref>PMID:21998747</ref>
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===Crystal Structure of Human 4-hydroxy-2-oxoglutarate Aldolase===
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==See Also==
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*[[Aldolase 3D structures|Aldolase 3D structures]]
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== References ==
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__TOC__
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(as it appears on PubMed at http://www.pubmed.gov), where 21998747 is the PubMed ID number.
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</StructureSection>
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{{ABSTRACT_PUBMED_21998747}}
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==About this Structure==
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[[3s5n]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3S5N OCA].
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==Reference==
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<ref group="xtra">PMID:021998747</ref><references group="xtra"/>
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[[Category: 4-hydroxy-2-oxoglutarate aldolase]]
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Lowther, W T.]]
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[[Category: Large Structures]]
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[[Category: Riedel, T J.]]
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[[Category: Lowther WT]]
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[[Category: Aldolase]]
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[[Category: Riedel TJ]]
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[[Category: Beta barrel]]
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[[Category: Hydroxyproline metabolism]]
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[[Category: Lyase]]
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Current revision

Crystal Structure of Human 4-hydroxy-2-oxoglutarate Aldolase

PDB ID 3s5n

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