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3sbt

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[[Image:3sbt.png|left|200px]]
 
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{{STRUCTURE_3sbt| PDB=3sbt | SCENE= }}
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==Crystal structure of a Aar2-Prp8 complex==
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<StructureSection load='3sbt' size='340' side='right'caption='[[3sbt]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
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===Crystal structure of a Aar2-Prp8 complex===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3sbt]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SBT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3SBT FirstGlance]. <br>
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{{ABSTRACT_PUBMED_21764848}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.799&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PGO:S-1,2-PROPANEDIOL'>PGO</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3sbt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3sbt OCA], [https://pdbe.org/3sbt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3sbt RCSB], [https://www.ebi.ac.uk/pdbsum/3sbt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3sbt ProSAT]</span></td></tr>
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[[3sbt]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SBT OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/PRP8_YEAST PRP8_YEAST] Required for pre-spliceosome formation, which is the first step of pre-mRNA splicing. This protein is associated with snRNP U5. Has a role in branch site-3' splice site selection. Associates with the branch site-3' splice 3'-exon region. Also has a role in cell cycle.<ref>PMID:2835658</ref> <ref>PMID:9150140</ref> <ref>PMID:12773561</ref> <ref>PMID:18779563</ref>
==See Also==
==See Also==
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*[[Pre-mRNA-splicing factor|Pre-mRNA-splicing factor]]
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*[[Pre-mRNA splicing factors 3D structures|Pre-mRNA splicing factors 3D structures]]
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== References ==
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==Reference==
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<references/>
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<ref group="xtra">PMID:021764848</ref><references group="xtra"/>
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__TOC__
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[[Category: Saccharomyces cerevisiae]]
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</StructureSection>
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[[Category: Holton, N.]]
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[[Category: Large Structures]]
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[[Category: Santos, K F.]]
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[[Category: Saccharomyces cerevisiae S288C]]
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[[Category: Wahl, M C.]]
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[[Category: Holton N]]
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[[Category: Weber, G.]]
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[[Category: Santos KF]]
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[[Category: Rnaseh like domain]]
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[[Category: Wahl MC]]
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[[Category: Splicing]]
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[[Category: Weber G]]
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[[Category: U5 snrnp assembly]]
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[[Category: Vhs like domain]]
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Current revision

Crystal structure of a Aar2-Prp8 complex

PDB ID 3sbt

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