3spk

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[[Image:3spk.png|left|200px]]
 
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{{STRUCTURE_3spk| PDB=3spk | SCENE= }}
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==Tipranavir in Complex with a Human Immunodeficiency Virus Type 1 Protease Variant==
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<StructureSection load='3spk' size='340' side='right'caption='[[3spk]], [[Resolution|resolution]] 1.24&Aring;' scene=''>
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===Tipranavir in Complex with a Human Immunodeficiency Virus Type 1 Protease Variant===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3spk]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SPK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3SPK FirstGlance]. <br>
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{{ABSTRACT_PUBMED_21871444}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.24&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=TPV:N-(3-{(1R)-1-[(6R)-4-HYDROXY-2-OXO-6-PHENETHYL-6-PROPYL-5,6-DIHYDRO-2H-PYRAN-3-YL]PROPYL}PHENYL)-5-(TRIFLUOROMETHYL)-2-PYRIDINESULFONAMIDE'>TPV</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3spk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3spk OCA], [https://pdbe.org/3spk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3spk RCSB], [https://www.ebi.ac.uk/pdbsum/3spk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3spk ProSAT]</span></td></tr>
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[[3spk]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SPK OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q000H7_9HIV1 Q000H7_9HIV1]
==See Also==
==See Also==
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*[[Virus protease|Virus protease]]
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*[[Immunodeficiency virus protease 3D structures|Immunodeficiency virus protease 3D structures]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:021871444</ref><references group="xtra"/>
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[[Category: HIV-1 retropepsin]]
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[[Category: Human immunodeficiency virus 1]]
[[Category: Human immunodeficiency virus 1]]
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[[Category: Brunzelle, J S.]]
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[[Category: Large Structures]]
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[[Category: Kovari, I A.]]
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[[Category: Brunzelle JS]]
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[[Category: Kovari, L C.]]
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[[Category: Kovari IA]]
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[[Category: Liu, Z.]]
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[[Category: Kovari LC]]
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[[Category: Wang, Y.]]
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[[Category: Liu Z]]
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[[Category: Hydorlase-hydorlase inhibitor complex]]
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[[Category: Wang Y]]
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[[Category: Multi-drug resistant hiv-1 protease]]
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[[Category: Tipranavir]]
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Current revision

Tipranavir in Complex with a Human Immunodeficiency Virus Type 1 Protease Variant

PDB ID 3spk

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