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3swl
From Proteopedia
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| - | [[Image:3swl.jpg|left|200px]] | ||
| - | < | + | ==Crystal Structure Analysis of H74A Mutant of Human CLIC1== |
| - | + | <StructureSection load='3swl' size='340' side='right'caption='[[3swl]], [[Resolution|resolution]] 2.35Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[3swl]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SWL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3SWL FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.35Å</td></tr> | |
| - | --> | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3swl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3swl OCA], [https://pdbe.org/3swl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3swl RCSB], [https://www.ebi.ac.uk/pdbsum/3swl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3swl ProSAT]</span></td></tr> |
| - | + | </table> | |
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/CLIC1_HUMAN CLIC1_HUMAN] Can insert into membranes and form chloride ion channels. Channel activity depends on the pH. Membrane insertion seems to be redox-regulated and may occur only under oxydizing conditions. Involved in regulation of the cell cycle.<ref>PMID:9139710</ref> <ref>PMID:10834939</ref> <ref>PMID:11195932</ref> <ref>PMID:11940526</ref> <ref>PMID:11978800</ref> <ref>PMID:11551966</ref> <ref>PMID:14613939</ref> | ||
| - | == | + | ==See Also== |
| - | + | *[[Ion channels 3D structures|Ion channels 3D structures]] | |
| - | + | == References == | |
| - | == | + | <references/> |
| - | + | __TOC__ | |
| + | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Achilonu IA]] |
| - | [[Category: | + | [[Category: Dirr HW]] |
| - | [[Category: | + | [[Category: Fanucchi S]] |
| - | [[Category: | + | [[Category: Fernandes MA]] |
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Current revision
Crystal Structure Analysis of H74A Mutant of Human CLIC1
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