This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
3t7l
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 3t7l is ON HOLD Authors: Chaikuad, A., Williams, E., Guo, K., Sanvitale, C., Berridge, G., Krojer, T., Muniz, J.R.C., Canning, P., Phillips, C., Shr...) |
|||
| (6 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of the FYVE domain of endofin (ZFYVE16) at 1.1A resolution== | |
| - | + | <StructureSection load='3t7l' size='340' side='right'caption='[[3t7l]], [[Resolution|resolution]] 1.09Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[3t7l]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T7L OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3T7L FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.09Å</td></tr> | |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3t7l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3t7l OCA], [https://pdbe.org/3t7l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3t7l RCSB], [https://www.ebi.ac.uk/pdbsum/3t7l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3t7l ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/ZFY16_HUMAN ZFY16_HUMAN] May be involved in regulating membrane trafficking in the endosomal pathway. Overexpression induces endosome aggregation. Required to target TOM1 to endosomes.<ref>PMID:11546807</ref> <ref>PMID:14613930</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Arrowsmith CH]] | ||
| + | [[Category: Berridge G]] | ||
| + | [[Category: Bountra C]] | ||
| + | [[Category: Bullock A]] | ||
| + | [[Category: Canning P]] | ||
| + | [[Category: Chaikuad A]] | ||
| + | [[Category: Edwards AM]] | ||
| + | [[Category: Guo K]] | ||
| + | [[Category: Krojer T]] | ||
| + | [[Category: Muniz JRC]] | ||
| + | [[Category: Phillips C]] | ||
| + | [[Category: Sanvitale C]] | ||
| + | [[Category: Shrestha A]] | ||
| + | [[Category: Weigelt J]] | ||
| + | [[Category: Williams E]] | ||
| + | [[Category: Von Delft F]] | ||
Current revision
Crystal structure of the FYVE domain of endofin (ZFYVE16) at 1.1A resolution
| |||||||||||
Categories: Homo sapiens | Large Structures | Arrowsmith CH | Berridge G | Bountra C | Bullock A | Canning P | Chaikuad A | Edwards AM | Guo K | Krojer T | Muniz JRC | Phillips C | Sanvitale C | Shrestha A | Weigelt J | Williams E | Von Delft F
