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3te3

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[[Image:3te3.png|left|200px]]
 
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==Coiled-coil oligomerization domain of the polycystin transient receptor potential channel PKD2L1==
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The line below this paragraph, containing "STRUCTURE_3te3", creates the "Structure Box" on the page.
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<StructureSection load='3te3' size='340' side='right'caption='[[3te3]], [[Resolution|resolution]] 2.69&Aring;' scene=''>
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3te3]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TE3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3TE3 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.694&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3te3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3te3 OCA], [https://pdbe.org/3te3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3te3 RCSB], [https://www.ebi.ac.uk/pdbsum/3te3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3te3 ProSAT]</span></td></tr>
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{{STRUCTURE_3te3| PDB=3te3 | SCENE= }}
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</table>
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== Function ==
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===Coiled-coil oligomerization domain of the polycystin transient receptor potential channel PKD2L1===
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[https://www.uniprot.org/uniprot/PK2L1_HUMAN PK2L1_HUMAN] Pore-forming subunit of a ciliary calcium channel that controls calcium concentration within primary cilia without affecting cytoplasmic calcium concentration. Forms a heterodimer with PKD1L1 in primary cilia and forms a calcium-permeant ciliary channel that regulates sonic hedgehog/SHH signaling and GLI2 transcription. May act as a sour taste receptor by forming a calcium channel with PKD1L3 in gustatory cells; however, its contribution to sour taste perception is unclear in vivo and may be indirect.<ref>PMID:10517637</ref> <ref>PMID:19812697</ref> <ref>PMID:23212381</ref> <ref>PMID:24336289</ref>
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== References ==
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<references/>
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</StructureSection>
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(as it appears on PubMed at http://www.pubmed.gov), where 22193359 is the PubMed ID number.
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{{ABSTRACT_PUBMED_22193359}}
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==About this Structure==
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[[3te3]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TE3 OCA].
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==Reference==
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<ref group="xtra">PMID:022193359</ref><references group="xtra"/>
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Molland, K M]]
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[[Category: Large Structures]]
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[[Category: Yernool, D A.]]
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[[Category: Molland KM]]
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[[Category: C-terminal cytoplasmic regulatory domain]]
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[[Category: Yernool DA]]
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[[Category: Metal transport]]
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[[Category: Oligomerization domain]]
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[[Category: Trimeric coiled-coil]]
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Current revision

Coiled-coil oligomerization domain of the polycystin transient receptor potential channel PKD2L1

PDB ID 3te3

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OCA

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