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3tup

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[[Image:3tup.png|left|200px]]
 
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==Crystal structure of human mitochondrial PheRS complexed with tRNAPhe in the active open state==
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The line below this paragraph, containing "STRUCTURE_3tup", creates the "Structure Box" on the page.
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<StructureSection load='3tup' size='340' side='right'caption='[[3tup]], [[Resolution|resolution]] 3.05&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3tup]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TUP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3TUP FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.05&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3tup FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tup OCA], [https://pdbe.org/3tup PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3tup RCSB], [https://www.ebi.ac.uk/pdbsum/3tup PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3tup ProSAT]</span></td></tr>
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{{STRUCTURE_3tup| PDB=3tup | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/SYFM_HUMAN SYFM_HUMAN] Catalyzes direct attachment of p-Tyr (Tyr) to tRNAPhe. Permits also, with a lower efficiency, the attachment of m-Tyr to tRNAPhe, thereby opening the way for delivery of the misacylated tRNA to the ribosome and incorporation of ROS-damaged amino acid into proteins.<ref>PMID:19549855</ref>
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===Crystal structure of human mitochondrial PheRS complexed with tRNAPhe in the active open state===
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==See Also==
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*[[Aminoacyl tRNA synthetase 3D structures|Aminoacyl tRNA synthetase 3D structures]]
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*[[Transfer RNA (tRNA)|Transfer RNA (tRNA)]]
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== References ==
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<references/>
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(as it appears on PubMed at http://www.pubmed.gov), where 22137894 is the PubMed ID number.
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__TOC__
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</StructureSection>
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{{ABSTRACT_PUBMED_22137894}}
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==About this Structure==
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[[3tup]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TUP OCA].
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==Reference==
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<ref group="xtra">PMID:022137894</ref><references group="xtra"/>
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Phenylalanine--tRNA ligase]]
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[[Category: Large Structures]]
[[Category: Thermus thermophilus]]
[[Category: Thermus thermophilus]]
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[[Category: Finarov, I.]]
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[[Category: Finarov I]]
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[[Category: Kessler, N.]]
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[[Category: Kessler N]]
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[[Category: Klipcan, L.]]
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[[Category: Klipcan L]]
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[[Category: Moor, N.]]
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[[Category: Moor N]]
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[[Category: Safro, M.]]
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[[Category: Safro M]]
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[[Category: Sukhanova, M.]]
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[[Category: Sukhanova M]]
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[[Category: Aminoacylation]]
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[[Category: Class ii aar]]
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[[Category: Ligase-rna complex]]
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[[Category: Mitochondria]]
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[[Category: Rrm fold]]
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Current revision

Crystal structure of human mitochondrial PheRS complexed with tRNAPhe in the active open state

PDB ID 3tup

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