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3tuv

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[[Image:3tuv.png|left|200px]]
 
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==Crystal structure of insulysin with bound ATP==
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The line below this paragraph, containing "STRUCTURE_3tuv", creates the "Structure Box" on the page.
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<StructureSection load='3tuv' size='340' side='right'caption='[[3tuv]], [[Resolution|resolution]] 2.27&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3tuv]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TUV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3TUV FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.27&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene></td></tr>
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{{STRUCTURE_3tuv| PDB=3tuv | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3tuv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tuv OCA], [https://pdbe.org/3tuv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3tuv RCSB], [https://www.ebi.ac.uk/pdbsum/3tuv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3tuv ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/IDE_RAT IDE_RAT] Plays a role in the cellular breakdown of insulin, IAPP, glucagon, bradykinin, kallidin and other peptides, and thereby plays a role in intercellular peptide signaling. Degrades amyloid formed by APP and IAPP.
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===Crystal structure of insulysin with bound ATP===
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==See Also==
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*[[Insulin-degrading enzyme 3D structures|Insulin-degrading enzyme 3D structures]]
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*[[RNA polymerase 3D structures|RNA polymerase 3D structures]]
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==About this Structure==
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__TOC__
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[[3tuv]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TUV OCA].
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</StructureSection>
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[[Category: Insulysin]]
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[[Category: Large Structures]]
[[Category: Rattus norvegicus]]
[[Category: Rattus norvegicus]]
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[[Category: Noinaj, N.]]
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[[Category: Noinaj N]]
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[[Category: Rodgers, D W.]]
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[[Category: Rodgers DW]]
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[[Category: Hydrolase]]
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[[Category: Hydrolyase]]
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[[Category: Peptidase]]
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[[Category: Thermolysin-like fold active site region]]
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Current revision

Crystal structure of insulysin with bound ATP

PDB ID 3tuv

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OCA

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