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3u09

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==Crystal structure of 3-ketoacyl-(acyl-carrier-protein) reductase (FabG)(G92D) from Vibrio cholerae==
==Crystal structure of 3-ketoacyl-(acyl-carrier-protein) reductase (FabG)(G92D) from Vibrio cholerae==
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<StructureSection load='3u09' size='340' side='right' caption='[[3u09]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
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<StructureSection load='3u09' size='340' side='right'caption='[[3u09]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3u09]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Vibrio_cholerae Vibrio cholerae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3U09 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3U09 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3u09]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Vibrio_cholerae_O1_biovar_El_Tor_str._N16961 Vibrio cholerae O1 biovar El Tor str. N16961]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3U09 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3U09 FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene><br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.75&#8491;</td></tr>
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<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">fabG, VC2021, VC_2021 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=666 Vibrio cholerae])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/3-oxoacyl-[acyl-carrier-protein]_reductase 3-oxoacyl-[acyl-carrier-protein] reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.100 1.1.1.100] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3u09 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3u09 OCA], [https://pdbe.org/3u09 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3u09 RCSB], [https://www.ebi.ac.uk/pdbsum/3u09 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3u09 ProSAT]</span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3u09 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3u09 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3u09 RCSB], [http://www.ebi.ac.uk/pdbsum/3u09 PDBsum]</span></td></tr>
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</table>
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<table>
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== Function ==
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[https://www.uniprot.org/uniprot/FABG_VIBCH FABG_VIBCH] Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
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==See Also==
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*[[Beta-hydroxyacyl-acyl carrier protein dehydratase 3D structures|Beta-hydroxyacyl-acyl carrier protein dehydratase 3D structures]]
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*[[Beta-ketoacyl carrier protein reductase 3D structures|Beta-ketoacyl carrier protein reductase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Vibrio cholerae]]
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[[Category: Large Structures]]
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[[Category: Anderson, W F.]]
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[[Category: Vibrio cholerae O1 biovar El Tor str. N16961]]
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[[Category: CSGID, Center for Structural Genomics of Infectious Diseases.]]
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[[Category: Anderson WF]]
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[[Category: Chruszcz, M.]]
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[[Category: Chruszcz M]]
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[[Category: Fratczak, Z.]]
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[[Category: Fratczak Z]]
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[[Category: Grabowski, M.]]
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[[Category: Grabowski M]]
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[[Category: Hou, J.]]
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[[Category: Hou J]]
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[[Category: Minor, W.]]
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[[Category: Minor W]]
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[[Category: Zheng,H.]]
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[[Category: Zheng H]]
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[[Category: Center for structural genomics of infectious disease]]
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[[Category: Csgid]]
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[[Category: Fabg]]
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[[Category: Oxidoreductase]]
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[[Category: Structural genomic]]
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[[Category: Vibrio cholerae]]
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Current revision

Crystal structure of 3-ketoacyl-(acyl-carrier-protein) reductase (FabG)(G92D) from Vibrio cholerae

PDB ID 3u09

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