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3ucs

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Current revision (10:22, 1 March 2024) (edit) (undo)
 
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<StructureSection load='3ucs' size='340' side='right'caption='[[3ucs]], [[Resolution|resolution]] 1.87&Aring;' scene=''>
<StructureSection load='3ucs' size='340' side='right'caption='[[3ucs]], [[Resolution|resolution]] 1.87&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3ucs]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Ecoli Ecoli] and [https://en.wikipedia.org/wiki/Klep3 Klep3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UCS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3UCS FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3ucs]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12] and [https://en.wikipedia.org/wiki/Klebsiella_pneumoniae_342 Klebsiella pneumoniae 342]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UCS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3UCS FirstGlance]. <br>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">cbpM, KPK_5158 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=507522 KLEP3]), b1000, cbpA, JW0985 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.87&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ucs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ucs OCA], [https://pdbe.org/3ucs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ucs RCSB], [https://www.ebi.ac.uk/pdbsum/3ucs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ucs ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ucs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ucs OCA], [https://pdbe.org/3ucs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ucs RCSB], [https://www.ebi.ac.uk/pdbsum/3ucs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ucs ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/CBPA_ECOLI CBPA_ECOLI]] DNA-binding protein that preferentially recognizes a curved DNA sequence. It is probably a functional analog of DnaJ; displays overlapping activities with DnaJ, but functions under different conditions, probably acting as a molecular chaperone in an adaptive response to environmental stresses other than heat shock. Lacks autonomous chaperone activity; binds native substrates and targets them for recognition by DnaK. Its activity is inhibited by the binding of CbpM.<ref>PMID:7601860</ref> <ref>PMID:8824642</ref>
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[https://www.uniprot.org/uniprot/B5Y388_KLEP3 B5Y388_KLEP3]
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== References ==
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<references/>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Ecoli]]
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[[Category: Escherichia coli K-12]]
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[[Category: Klep3]]
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[[Category: Klebsiella pneumoniae 342]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Structural genomic]]
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[[Category: Cygler M]]
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[[Category: Cygler, M]]
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[[Category: Ekiel I]]
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[[Category: Ekiel, I]]
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[[Category: Sarraf NS]]
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[[Category: Sarraf, N S]]
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[[Category: Shi R]]
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[[Category: Shi, R]]
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[[Category: Bsgi]]
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[[Category: Chaperone]]
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[[Category: Co-chaperone regulation]]
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[[Category: Protein-protein complex]]
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Current revision

Crystal structure of the complex between CBPA J-domain and CBPM

PDB ID 3ucs

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