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3uh1

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[[Image:3uh1.png|left|200px]]
 
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{{STRUCTURE_3uh1| PDB=3uh1 | SCENE= }}
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==Crystal Structure of Saccharopine Dehydrogenase from Saccharomyces cerevisiae with bound saccharopine and NADH==
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<StructureSection load='3uh1' size='340' side='right'caption='[[3uh1]], [[Resolution|resolution]] 2.17&Aring;' scene=''>
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===Crystal Structure of Saccharopine Dehydrogenase from Saccharomyces cerevisiae with bound saccharopine and NADH===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[3uh1]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UH1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3UH1 FirstGlance]. <br>
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{{ABSTRACT_PUBMED_22243403}}
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.17&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NAI:1,4-DIHYDRONICOTINAMIDE+ADENINE+DINUCLEOTIDE'>NAI</scene>, <scene name='pdbligand=SHR:N-(5-AMINO-5-CARBOXYPENTYL)GLUTAMIC+ACID'>SHR</scene></td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3uh1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3uh1 OCA], [https://pdbe.org/3uh1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3uh1 RCSB], [https://www.ebi.ac.uk/pdbsum/3uh1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3uh1 ProSAT]</span></td></tr>
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[[3uh1]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UH1 OCA].
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</table>
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== Function ==
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==Reference==
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[https://www.uniprot.org/uniprot/LYS1_YEAST LYS1_YEAST] Catalyzes the NAD(+)-dependent cleavage of saccharopine to L-lysine and 2-oxoglutarate.
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<ref group="xtra">PMID:022243403</ref><references group="xtra"/>
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__TOC__
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[[Category: Saccharomyces cerevisiae]]
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</StructureSection>
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[[Category: Andi, B.]]
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[[Category: Large Structures]]
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[[Category: Bobyk, K D.]]
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[[Category: Saccharomyces cerevisiae S288C]]
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[[Category: Cook, P F.]]
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[[Category: Andi B]]
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[[Category: Kumar, V P.]]
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[[Category: Bobyk KD]]
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[[Category: Thomas, L M.]]
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[[Category: Cook PF]]
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[[Category: West, A H.]]
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[[Category: Kumar VP]]
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[[Category: Enzyme mechanism]]
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[[Category: Thomas LM]]
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[[Category: Lysine biosynthesis]]
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[[Category: West AH]]
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[[Category: Oxidoreductase]]
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[[Category: Proton shuttle]]
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[[Category: Saccharopine and nad binding]]
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Current revision

Crystal Structure of Saccharopine Dehydrogenase from Saccharomyces cerevisiae with bound saccharopine and NADH

PDB ID 3uh1

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