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3unw
From Proteopedia
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==Crystal Structure of Human GAC in Complex with Glutamate== | ==Crystal Structure of Human GAC in Complex with Glutamate== | ||
| - | <StructureSection load='3unw' size='340' side='right' caption='[[3unw]], [[Resolution|resolution]] 2.56Å' scene=''> | + | <StructureSection load='3unw' size='340' side='right'caption='[[3unw]], [[Resolution|resolution]] 2.56Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3unw]] is a 4 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[3unw]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UNW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3UNW FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.56Å</td></tr> |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GLU:GLUTAMIC+ACID'>GLU</scene></td></tr> | |
| - | <tr id=' | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3unw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3unw OCA], [https://pdbe.org/3unw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3unw RCSB], [https://www.ebi.ac.uk/pdbsum/3unw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3unw ProSAT]</span></td></tr> |
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| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
| - | + | == Function == | |
| - | = | + | [https://www.uniprot.org/uniprot/GLSK_HUMAN GLSK_HUMAN] Catalyzes the first reaction in the primary pathway for the renal catabolism of glutamine. Plays a role in maintaining acid-base homeostasis. Regulates the levels of the neurotransmitter glutamate in the brain. Isoform 2 lacks catalytic activity. |
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==See Also== | ==See Also== | ||
*[[Glutaminase|Glutaminase]] | *[[Glutaminase|Glutaminase]] | ||
| - | + | *[[Glutaminase 3D structures|Glutaminase 3D structures]] | |
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: Glutaminase]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: Cheng | + | [[Category: Large Structures]] |
| - | [[Category: DeLaBarre | + | [[Category: Cheng F]] |
| - | [[Category: Gao | + | [[Category: DeLaBarre B]] |
| - | [[Category: Gross | + | [[Category: Gao Y]] |
| - | [[Category: Hurov | + | [[Category: Gross S]] |
| - | [[Category: Jha | + | [[Category: Hurov J]] |
| - | [[Category: Jiang | + | [[Category: Jha A]] |
| - | [[Category: Song | + | [[Category: Jiang F]] |
| - | [[Category: Wie | + | [[Category: Song JJ]] |
| - | + | [[Category: Wie W]] | |
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Current revision
Crystal Structure of Human GAC in Complex with Glutamate
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Categories: Homo sapiens | Large Structures | Cheng F | DeLaBarre B | Gao Y | Gross S | Hurov J | Jha A | Jiang F | Song JJ | Wie W
