3uo9
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal Structure of Human GAC in Complex with Glutamate and BPTES== | |
| + | <StructureSection load='3uo9' size='340' side='right'caption='[[3uo9]], [[Resolution|resolution]] 2.30Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[3uo9]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3UO9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3UO9 FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=04A:N,N-[SULFANEDIYLBIS(ETHANE-2,1-DIYL-1,3,4-THIADIAZOLE-5,2-DIYL)]BIS(2-PHENYLACETAMIDE)'>04A</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3uo9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3uo9 OCA], [https://pdbe.org/3uo9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3uo9 RCSB], [https://www.ebi.ac.uk/pdbsum/3uo9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3uo9 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/GLSK_HUMAN GLSK_HUMAN] Catalyzes the first reaction in the primary pathway for the renal catabolism of glutamine. Plays a role in maintaining acid-base homeostasis. Regulates the levels of the neurotransmitter glutamate in the brain. Isoform 2 lacks catalytic activity. | ||
| - | + | ==See Also== | |
| - | + | *[[Glutaminase 3D structures|Glutaminase 3D structures]] | |
| - | + | __TOC__ | |
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Cheng F]] | ||
| + | [[Category: DeLaBarre B]] | ||
| + | [[Category: Gao Y]] | ||
| + | [[Category: Gross S]] | ||
| + | [[Category: Hurov JB]] | ||
| + | [[Category: Jha A]] | ||
| + | [[Category: Jiang F]] | ||
| + | [[Category: Song JJ]] | ||
| + | [[Category: Wei W]] | ||
Current revision
Crystal Structure of Human GAC in Complex with Glutamate and BPTES
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Categories: Homo sapiens | Large Structures | Cheng F | DeLaBarre B | Gao Y | Gross S | Hurov JB | Jha A | Jiang F | Song JJ | Wei W
