3v8f

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[[Image:3v8f.jpg|left|200px]]
 
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==Crystal structure of crosslinked GltPh V216C-M385C mutant==
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The line below this paragraph, containing "STRUCTURE_3v8f", creates the "Structure Box" on the page.
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<StructureSection load='3v8f' size='340' side='right'caption='[[3v8f]], [[Resolution|resolution]] 3.80&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3v8f]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_horikoshii_OT3 Pyrococcus horikoshii OT3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3V8F OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3V8F FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.8&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ASP:ASPARTIC+ACID'>ASP</scene>, <scene name='pdbligand=HG:MERCURY+(II)+ION'>HG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
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{{STRUCTURE_3v8f| PDB=3v8f | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3v8f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3v8f OCA], [https://pdbe.org/3v8f PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3v8f RCSB], [https://www.ebi.ac.uk/pdbsum/3v8f PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3v8f ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/GLT_PYRHO GLT_PYRHO] Sodium-dependent, high-affinity amino acid transporter that mediates aspartate uptake (PubMed:17435767, PubMed:19380583, PubMed:17230192, Ref.11). Has only very low glutamate transport activity (PubMed:19380583, PubMed:17230192). Functions as a symporter that transports one amino acid molecule together with two or three Na(+) ions, resulting in electrogenic transport (PubMed:17435767, PubMed:19380583, Ref.11). Na(+) binding enhances the affinity for aspartate (PubMed:19380583, Ref.11). Mediates Cl(-) flux that is not coupled to amino acid transport; this avoids the accumulation of negative charges due to aspartate and Na(+) symport (PubMed:17435767). In contrast to mammalian homologs, transport does not depend on pH or K(+) ions (PubMed:19380583).<ref>PMID:17230192</ref> <ref>PMID:17435767</ref> <ref>PMID:19380583</ref> [PDB:4P19]
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===Crystal structure of crosslinked GltPh V216C-M385C mutant===
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==See Also==
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*[[Symporter 3D structures|Symporter 3D structures]]
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== References ==
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==About this Structure==
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<references/>
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[[3v8f]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Pyrococcus_horikoshii Pyrococcus horikoshii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3V8F OCA].
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__TOC__
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[[Category: Pyrococcus horikoshii]]
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</StructureSection>
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[[Category: Boudker, O.]]
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[[Category: Large Structures]]
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[[Category: Verdon, G.]]
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[[Category: Pyrococcus horikoshii OT3]]
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[[Category: L-arpartate]]
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[[Category: Boudker O]]
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[[Category: Membrane]]
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[[Category: Verdon G]]
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[[Category: Sodium ion]]
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[[Category: Transport protein]]
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Current revision

Crystal structure of crosslinked GltPh V216C-M385C mutant

PDB ID 3v8f

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