This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
3v99
From Proteopedia
(Difference between revisions)
| (6 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==S663D Stable-5-LOX in complex with Arachidonic Acid== | |
| - | + | <StructureSection load='3v99' size='340' side='right'caption='[[3v99]], [[Resolution|resolution]] 2.25Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[3v99]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3V99 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3V99 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.252Å</td></tr> | |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACD:ARACHIDONIC+ACID'>ACD</scene>, <scene name='pdbligand=FE2:FE+(II)+ION'>FE2</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3v99 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3v99 OCA], [https://pdbe.org/3v99 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3v99 RCSB], [https://www.ebi.ac.uk/pdbsum/3v99 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3v99 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/LOX5_HUMAN LOX5_HUMAN] Catalyzes the first step in leukotriene biosynthesis, and thereby plays a role in inflammatory processes.<ref>PMID:21233389</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Bartlett SG]] | ||
| + | [[Category: Boeglin WE]] | ||
| + | [[Category: Brash AR]] | ||
| + | [[Category: Gilbert NC]] | ||
| + | [[Category: Neau DB]] | ||
| + | [[Category: Newcomer ME]] | ||
| + | [[Category: Rui Z]] | ||
| + | [[Category: Waight M]] | ||
Current revision
S663D Stable-5-LOX in complex with Arachidonic Acid
| |||||||||||
Categories: Homo sapiens | Large Structures | Bartlett SG | Boeglin WE | Brash AR | Gilbert NC | Neau DB | Newcomer ME | Rui Z | Waight M
