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3vdn

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Current revision (10:35, 1 March 2024) (edit) (undo)
 
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<StructureSection load='3vdn' size='340' side='right'caption='[[3vdn]], [[Resolution|resolution]] 2.55&Aring;' scene=''>
<StructureSection load='3vdn' size='340' side='right'caption='[[3vdn]], [[Resolution|resolution]] 2.55&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3vdn]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/"streptomyces_hygroscopicus_subsp._limoneus"_shibata_et_al._1973 "streptomyces hygroscopicus subsp. limoneus" shibata et al. 1973]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VDN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3VDN FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3vdn]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_hygroscopicus_subsp._limoneus Streptomyces hygroscopicus subsp. limoneus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VDN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3VDN FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.55&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3vdm|3vdm]]</div></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">vldE ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=264445 "Streptomyces hygroscopicus subsp. limoneus" Shibata et al. 1973])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3vdn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vdn OCA], [https://pdbe.org/3vdn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3vdn RCSB], [https://www.ebi.ac.uk/pdbsum/3vdn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3vdn ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3vdn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vdn OCA], [https://pdbe.org/3vdn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3vdn RCSB], [https://www.ebi.ac.uk/pdbsum/3vdn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3vdn ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/VLDE_STRHL VLDE_STRHL] Involved in the biosynthesis of the antifungal agent validamycin A (PubMed:16725283). Catalyzes the condensation between GDP-valienol and validamine 7-phosphate via a nonglycosidic C-N bond formation to yield validoxylamine A 7'-phosphate (PubMed:21766819).<ref>PMID:16725283</ref> <ref>PMID:21766819</ref>
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==See Also==
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*[[Glycosyltransferase 3D structures|Glycosyltransferase 3D structures]]
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== References ==
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<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Streptomyces hygroscopicus subsp. limoneus shibata et al. 1973]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Asamizu, S]]
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[[Category: Streptomyces hygroscopicus subsp. limoneus]]
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[[Category: Cavalier, M C]]
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[[Category: Asamizu S]]
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[[Category: Lee, Y H]]
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[[Category: Cavalier MC]]
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[[Category: Mahmud, T]]
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[[Category: Lee Y-H]]
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[[Category: Neau, D]]
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[[Category: Mahmud T]]
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[[Category: Yim, Y S]]
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[[Category: Neau D]]
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[[Category: Rossmann fold]]
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[[Category: Yim Y-S]]
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[[Category: Transferase]]
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Current revision

Crystal Structure of VldE, the pseudo-glycosyltransferase, in complex with GDP

PDB ID 3vdn

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