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4dy0

From Proteopedia

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[[Image:4dy0.jpg|left|200px]]
 
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{{STRUCTURE_4dy0| PDB=4dy0 | SCENE= }}
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==Crystal structure of native protease nexin-1 with heparin==
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<StructureSection load='4dy0' size='340' side='right'caption='[[4dy0]], [[Resolution|resolution]] 2.35&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4dy0]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DY0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4DY0 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.35&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=IDS:2-O-SULFO-ALPHA-L-IDOPYRANURONIC+ACID'>IDS</scene>, <scene name='pdbligand=SGN:N,O6-DISULFO-GLUCOSAMINE'>SGN</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4dy0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4dy0 OCA], [https://pdbe.org/4dy0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4dy0 RCSB], [https://www.ebi.ac.uk/pdbsum/4dy0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4dy0 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/GDN_HUMAN GDN_HUMAN] Serine protease inhibitor with activity toward thrombin, trypsin, and urokinase. Promotes neurite extension by inhibiting thrombin. Binds heparin.
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===Crystal structure of native protease nexin-1 with heparin===
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==See Also==
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*[[Serpin 3D structures|Serpin 3D structures]]
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{{ABSTRACT_PUBMED_22618708}}
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__TOC__
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</StructureSection>
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==About this Structure==
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[[4dy0]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus] and [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DY0 OCA].
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==Reference==
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<ref group="xtra">PMID:022618708</ref><references group="xtra"/>
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[[Category: Bos taurus]]
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Huntington, J A.]]
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[[Category: Large Structures]]
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[[Category: Li, W.]]
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[[Category: Huntington JA]]
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[[Category: Cell surface]]
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[[Category: Li W]]
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[[Category: Hydrolase inhibitor]]
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[[Category: Protease inhibitor]]
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[[Category: Serpin]]
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[[Category: Thrombin]]
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Current revision

Crystal structure of native protease nexin-1 with heparin

PDB ID 4dy0

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