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4dz0

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[[Image:4dz0.jpg|left|200px]]
 
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{{STRUCTURE_4dz0| PDB=4dz0 | SCENE= }}
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==Crystal structure of the Cu-adduct of human H-Ferritin variant MIC1 labeled with a dansyl fluorophore==
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<StructureSection load='4dz0' size='340' side='right'caption='[[4dz0]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4dz0]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DZ0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4DZ0 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AEN:5-(1-SULFONAPHTHYL)-ACETYLAMINO-ETHYLAMINE'>AEN</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4dz0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4dz0 OCA], [https://pdbe.org/4dz0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4dz0 RCSB], [https://www.ebi.ac.uk/pdbsum/4dz0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4dz0 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/FRIH_HUMAN FRIH_HUMAN] Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney (By similarity).
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===Crystal structure of the Cu-adduct of human H-Ferritin variant MIC1 labeled with a dansyl fluorophore===
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==See Also==
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*[[Ferritin 3D structures|Ferritin 3D structures]]
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__TOC__
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==About this Structure==
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</StructureSection>
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[[4dz0]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DZ0 OCA].
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[[Category: Ferroxidase]]
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Huard, D J.E.]]
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[[Category: Large Structures]]
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[[Category: Tezcan, F A.]]
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[[Category: Huard DJE]]
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[[Category: Four-helix bundle]]
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[[Category: Tezcan FA]]
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[[Category: Oxidoreductase]]
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Current revision

Crystal structure of the Cu-adduct of human H-Ferritin variant MIC1 labeled with a dansyl fluorophore

PDB ID 4dz0

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