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4ffm

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{{STRUCTURE_4ffm| PDB=4ffm | SCENE= }}
 
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===PylC in complex with L-lysine-Ne-D-ornithine (cocrystallized with L-lysine-Ne-D-ornithine)===
 
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{{ABSTRACT_PUBMED_22985965}}
 
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==About this Structure==
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==PylC in complex with L-lysine-Ne-D-ornithine (cocrystallized with L-lysine-Ne-D-ornithine)==
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[[4ffm]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Methanosarcina_barkeri_str._fusaro Methanosarcina barkeri str. fusaro]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FFM OCA].
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<StructureSection load='4ffm' size='340' side='right'caption='[[4ffm]], [[Resolution|resolution]] 1.91&Aring;' scene=''>
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[[Category: Methanosarcina barkeri str. fusaro]]
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== Structural highlights ==
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[[Category: Bacher, A.]]
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<table><tr><td colspan='2'>[[4ffm]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Methanosarcina_barkeri_str._Fusaro Methanosarcina barkeri str. Fusaro]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FFM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4FFM FirstGlance]. <br>
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[[Category: Beck, P.]]
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.91&#8491;</td></tr>
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[[Category: Groll, M.]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=0TF:N~6~-D-ORNITHYL-L-LYSINE'>0TF</scene>, <scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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[[Category: List, A.]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ffm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ffm OCA], [https://pdbe.org/4ffm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ffm RCSB], [https://www.ebi.ac.uk/pdbsum/4ffm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ffm ProSAT]</span></td></tr>
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[[Category: Quitterer, F.]]
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</table>
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[[Category: Amino acid]]
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== Function ==
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[[Category: Atp-binding]]
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[https://www.uniprot.org/uniprot/PYLC_METBF PYLC_METBF] Is required for the biosynthesis of pyrrolysine (By similarity). Catalyzes the ATP-dependent ligation between (3R)-3-methyl-D-ornithine and L-lysine, leading to (3R)-3-methyl-D-ornithyl-N6-L-lysine (Probable).[UniProtKB:Q8TUC0]<ref>PMID:22985965</ref>
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[[Category: Atp-grasp fold]]
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== References ==
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[[Category: Biosynthesis of pyrrolysine]]
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<references/>
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[[Category: Cytosol]]
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__TOC__
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[[Category: Isopeptide bond formation]]
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</StructureSection>
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[[Category: L-lysine and 3r-methyl-d-ornithine]]
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[[Category: Large Structures]]
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[[Category: Ligase]]
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[[Category: Methanosarcina barkeri str. Fusaro]]
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[[Category: Ligase-product complex]]
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[[Category: Bacher A]]
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[[Category: Beck P]]
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[[Category: Groll M]]
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[[Category: List A]]
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[[Category: Quitterer F]]

Current revision

PylC in complex with L-lysine-Ne-D-ornithine (cocrystallized with L-lysine-Ne-D-ornithine)

PDB ID 4ffm

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