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4ffp

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Current revision (11:16, 1 March 2024) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 4ffp is ON HOLD until Paper Publication
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==PylC in complex with L-lysine-Ne-D-ornithine (cocrystallized with L-lysine and D-ornithine)==
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<StructureSection load='4ffp' size='340' side='right'caption='[[4ffp]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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Authors: Quitterer, F., List, A., Beck, P., Bacher, A., Groll, M.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4ffp]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Methanosarcina_barkeri_str._Fusaro Methanosarcina barkeri str. Fusaro]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FFP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4FFP FirstGlance]. <br>
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Description: PylC in complex with L-lysine-Ne-D-ornithine (cocrystallized with L-lysine and D-ornithine)
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=0TF:N~6~-D-ORNITHYL-L-LYSINE'>0TF</scene>, <scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ffp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ffp OCA], [https://pdbe.org/4ffp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ffp RCSB], [https://www.ebi.ac.uk/pdbsum/4ffp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ffp ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/PYLC_METBF PYLC_METBF] Is required for the biosynthesis of pyrrolysine (By similarity). Catalyzes the ATP-dependent ligation between (3R)-3-methyl-D-ornithine and L-lysine, leading to (3R)-3-methyl-D-ornithyl-N6-L-lysine (Probable).[UniProtKB:Q8TUC0]<ref>PMID:22985965</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Methanosarcina barkeri str. Fusaro]]
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[[Category: Bacher A]]
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[[Category: Beck P]]
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[[Category: Groll M]]
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[[Category: List A]]
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[[Category: Quitterer F]]

Current revision

PylC in complex with L-lysine-Ne-D-ornithine (cocrystallized with L-lysine and D-ornithine)

PDB ID 4ffp

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