This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.


Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


4ffp

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (11:16, 1 March 2024) (edit) (undo)
 
(2 intermediate revisions not shown.)
Line 1: Line 1:
-
{{STRUCTURE_4ffp| PDB=4ffp | SCENE= }}
 
-
===PylC in complex with L-lysine-Ne-D-ornithine (cocrystallized with L-lysine and D-ornithine)===
 
-
{{ABSTRACT_PUBMED_22985965}}
 
-
==About this Structure==
+
==PylC in complex with L-lysine-Ne-D-ornithine (cocrystallized with L-lysine and D-ornithine)==
-
[[4ffp]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Methanosarcina_barkeri_str._fusaro Methanosarcina barkeri str. fusaro]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FFP OCA].
+
<StructureSection load='4ffp' size='340' side='right'caption='[[4ffp]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
-
[[Category: Methanosarcina barkeri str. fusaro]]
+
== Structural highlights ==
-
[[Category: Bacher, A.]]
+
<table><tr><td colspan='2'>[[4ffp]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Methanosarcina_barkeri_str._Fusaro Methanosarcina barkeri str. Fusaro]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FFP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4FFP FirstGlance]. <br>
-
[[Category: Beck, P.]]
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
-
[[Category: Groll, M.]]
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=0TF:N~6~-D-ORNITHYL-L-LYSINE'>0TF</scene>, <scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
-
[[Category: List, A.]]
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ffp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ffp OCA], [https://pdbe.org/4ffp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ffp RCSB], [https://www.ebi.ac.uk/pdbsum/4ffp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ffp ProSAT]</span></td></tr>
-
[[Category: Quitterer, F.]]
+
</table>
-
[[Category: Amino acid]]
+
== Function ==
-
[[Category: Atp-binding]]
+
[https://www.uniprot.org/uniprot/PYLC_METBF PYLC_METBF] Is required for the biosynthesis of pyrrolysine (By similarity). Catalyzes the ATP-dependent ligation between (3R)-3-methyl-D-ornithine and L-lysine, leading to (3R)-3-methyl-D-ornithyl-N6-L-lysine (Probable).[UniProtKB:Q8TUC0]<ref>PMID:22985965</ref>
-
[[Category: Atp-grasp fold]]
+
== References ==
-
[[Category: Biosynthesis of pyrrolysine]]
+
<references/>
-
[[Category: Cytosol]]
+
__TOC__
-
[[Category: Isopeptide bond formation]]
+
</StructureSection>
-
[[Category: L-lysine and 3r-methyl-d-ornithine]]
+
[[Category: Large Structures]]
-
[[Category: Ligase]]
+
[[Category: Methanosarcina barkeri str. Fusaro]]
-
[[Category: Ligase-product complex]]
+
[[Category: Bacher A]]
 +
[[Category: Beck P]]
 +
[[Category: Groll M]]
 +
[[Category: List A]]
 +
[[Category: Quitterer F]]

Current revision

PylC in complex with L-lysine-Ne-D-ornithine (cocrystallized with L-lysine and D-ornithine)

PDB ID 4ffp

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools